Expert Details

Expert in Biochemistry; Infectious Disease Diagnostics Technology and Running of COVID-19 Clinical Diagnostics Lab

Expert ID: 736476 California, USA

Request Expert

Expert, PhD, is an Assistant Adjunct Professor in the Department of Microbiology and Immunology at a university in California. Her work is focused on the development of new methods for infectious disease diagnostics, with particular focus on diagnostic uses of CRISPR technology. She is an expert in the use of metagenomic Next Generation Sequencing in clinical samples for discovery and diagnostic purposes, and has coauthored numerous publications in this area.

From March to November 2020, Expert developed and lead the Biohub/UCSF COVID19 clinical testing facility known as CLIAHUB, processing over 1,000 SARS-CoV2 PCR tests per day for Public Health Departments across California.

Available for panels, in depth interviews, and surveys only.

Expert may consult nationally and internationally, and is also local to the following cities: San Francisco, CA - Los Angeles, CA - San Diego, CA

Request Expert

Education

Year Degree Subject Institution
Year: 2012 Degree: PhD Subject: Chemistry and Chemical Biology Institution: University of California San Francisco
Year: 2003 Degree: AB Subject: Molecular, Cellular and Developmental Biology Institution: Bryn Mawr College

Work History

Years Employer Title Department Responsibilities
Years: 2019 to Present Employer: Undisclosed Title: Assistant Adjunct Professor Department: Dept. of Microbiology and Immunology Responsibilities: Member, UCSF COVID-19 Research Coordination Task Force
Years: 2016 to 2020 Employer: Chan Zuckerberg Biohub Title: Group Leader Department: Infectious Disease Initiative Responsibilities: Lead the effort to launch the CLIAhub COVID19 testing lab, a collaboration between CZ Biohub and UCSF.
• Lead the development and validation of our RT-PCR LDT (under review for FDA EUA authorization) which occurred over the course of 8 days, launching March 20th 2020
• Grew the lab to 8 RNA extraction stations, 2 shifts, and over 1,000 samples/day processed with a workforce of over 100 volunteer scientists
• Transitioned from leading a volunteer workforce to managing a staff of 12 Laboratory Specialists
• Built and maintained relationships with over 20 California county Public Health departments for which CLIAhub provided free testing
• Provided RT-PCR COVID19 testing for numerous community clinical research studies at UCSF

February 2017 – February 2020
Built and lead a collaborative team of 4 to bring CRISPR-based infectious disease diagnostics to the Biohub.
• Developed and optimized the FLASH (Finding Low Abundance Sequences by Hybridization) method for targeted-enrichment NGS as well as more rapid, sequencing-free methods.
• Lead Biohub efforts to use sequencing to detect and analyze outbreaks of hospital-acquired infections in collaboration with UCSF’s Infection Control team.
Years: 2016 to 2017 Employer: Joe DeRisi’s Lab, University of California San Francisco (UCSF) Title: Chan Zuckerberg Biohub Postdoctoral Scholar Department: Responsibilities:
Years: 2014 to 2016 Employer: Joe DeRisi’s Lab, University of California San Francisco (UCSF) Title: Postdoctoral Scholar/HHMI Research Associate Department: Responsibilities: Produced recombinant CRISPR/Cas9 ribonucleoprotein complex and developed Cas9-based tools for depleting abundant sequences and enriching rare sequences in NGS libraries. Developed a method for plasmid-free genome editing in the malaria parasite P. falciparum. Trained and managed 3 technicians, mentored numerous students and two TechWomen interns, supervised journal club, assisted with Genomics Bootcamps run by the UCSF Development Office.
Years: 2012 to 2013 Employer: German Center for Neurodegenerative Diseases (DZNE) Title: Postdoc Department: Responsibilities: C. elegans proteomics.

Career Accomplishments

Awards / Recognition
Dean’s Recognition for Excellence in Teaching Award from UCSF’s School of Pharmacy
Publications and Patents Summary
[Selected] Oral Presentations:
• Next Generation Dx Virtual Summit
• Association for Molecular Pathology meeting
• American Society for Microbiology’s ASM Microbe meeting, Mini-Conference on Microbial Genomics and Public Health
• Wellcome Genome Campus Retreat on CRISPR Approaches for Apicomplexans
• Cold Spring Harbor Laboratory meeting on Genome Engineering: The CRISPR/Cas Revolution
• Keystone meeting on Precision Genome Engineering and Synthetic Biology
• 7th General Meeting of the International Proteolysis Society

[Selected] Publications: 22

Patents Filed: 2

Additional Experience

Training / Seminars
Adobe Illustrator Workshop TA, UCSF Office of Career and Professional Development, 2011-16. 

Graduate of UCSF’s “Idea to IPO” course on the business of biotechnology, 2008.
Marketing Experience
Contract editor in biochemistry and related fields for American Journal Experts.
Other Relevant Experience
Professional Mentor to Emerging Leaders from developing countries for the U.S. Department of State’s TechWomen program, 2015-present. Each year this consists of a month of intensive mentoring and training in basic lab techniques, including CRISPR, cloning, NGS. Also served on Selection Committees.



Fields of Expertise

Request Expert

Dev Tool:

Request: expert/biochemistry-infectious-disease-diagnostics-technology-and-running-of-covid-19-clinical-diagnostics-lab
Matched Rewrite Rule: expert/([^/]+)(?:/([0-9]+))?/?$
Matched Rewrite Query: experts=biochemistry-infectious-disease-diagnostics-technology-and-running-of-covid-19-clinical-diagnostics-lab&page=
Loaded Template: single-experts.php