Expert in Bionanosciences, Nanomaterial interfacing & targeting, Cell biology & biophysics, Molecular imaging, Microscopy
In addition to his expertise in nanomaterials interfacing with biomolecules the expert has extensive experience in single molecule detection, ultra-high resolution fluorescence imaging including super-resolution imaging and single particle tracking in living cells and biological tissues. In particular, the expert continuously develops new fluorescent probes and imaging strategies to study biomolecules in their native environment and map cellular structures with nanometer resolution. The expert has firsthand experience in fluorescence microscopy including confocal, stage scanning, TIRF, wide field, and PALM/STORM microsopy, optics, fluorescent probes photophysics, protein engineering, protein expression and purification, protein and DNA bioconjugation, genetic engineering and molecular biology, cell culture, biochemistry of cell membranes, intracellular targeting and delivery techniques, fluorescence quantification diffusion analysis and image treatment.
The expert multidisciplinary research has attracted financial support by the National Institut of Health (NIH), the National Science Foundation (NSF), the Marie-Curie Actions and the European Molecular Biology organization (EMBO).
Expert may consult nationally and internationally, and is also local to the following cities: Los Angeles, California - Long Beach, California - Santa Ana, California - Anaheim, California - Riverside, California - Bakersfield, California - Glendale, California - Huntington Beach, California - San Bernardino, California - Oxnard, California
|Year: 2007||Degree: PhD||Subject: Biochemistry and Molecular Biology||Institution: University of California Los Angeles|
|Year: 1999||Degree: BSc||Subject: Biomedical Sciences||Institution: Nottingham Trent University|
|Year: 1996||Degree: Diplome Universitaire de Technologie||Subject: Genie Biologique, Analyses Biologiques et Biochimiques||Institution: Institut Universitaire de Technologie Clermont-Ferrand|
|Years: 2019 to Present||Employer: Undisclosed||Title: Associate Professor||Department: Biological Sciences, Chemistry and Physics and Astronomy||Responsibilities: Principal Investigator of the Single Molecule Biophotonics Group|
|Years: 2011 to 2019||Employer: University of Southern California||Title: Assistant Professor||Department: Biological Sciences, Chemistry and Physics and Astronomy||Responsibilities: Principal Investigator of the Single Molecule Biophotonics Group|
|Years: 2007 to 2011||Employer: Ecole Normale Superieure||Title: Marie-Curie and EMBO Post-doctoral Fellow||Department: Departement de Physique, Groupe Optique et Biologie||Responsibilities: Expert develops fluorescent probes (dyes, fluorescent proteins, quantum dots…) and microscopy techniques for single molecule imaging and tracking in living cells and organisms.|
|Years: 2002 to 2007||Employer: University of California, Los Angeles||Title: Research Assistant||Department: Department of Chemistry and Biochemistry||Responsibilities: Expert develops surface and colloidal chemistry's of semiconductor quantum dots for fluorescence imaging of biological samples. He designs and build optical set up for high sensitivity fluorescent microscopy and engineers proteins and high affinity pairs for single molecule microscopy in living cells. Expert also develops cell models for single molecule imaging and tracking with quantum dots and studies the diffusional dynamics of membrane proteins associated with micro-domains in living cells.
|Years: 2001 to 2002||Employer: University of California, Berkeley||Title: Research Assistant||Department: Biophysics||Responsibilities: Expert develops surface chemistry of nanomaterials and analytical techniques and processes for colloidal characterization of bio-compatible quantum dots. Expert also characterize quantum dot by single molecule fluorescence microscopy.|
|Years: 1999 to 2001||Employer: Lawrence Berkeley National Laboratory||Title: Research assistant||Department: Material Sciences and Physical Biosciences Division||Responsibilities: Expert synthesizes semiconductor quantum dot probes and characterizes their photo-physical properties. He also develops bio-compatible surface chemistry and bio-labeling strategies.|
|Years: 1997 to 1998||Employer: Hoffmann-La Roche||Title: Research assistant||Department: Pharma Division||Responsibilities: Expert performs R&D on fluorescence techniques and labeling of recombinant proteins (tumor necrosis factor, interferon…) and develops a fluorescence linked immuno binding assays for quality control analysis of biotechnological products.
Expert works under Good Manipulating Practices and Good Laboratory Practices (GMP/GLP).
|Years||Country / Region||Summary|
|Years: 1999 to 2007||Country / Region: USA||Summary: The expert was a research assistant at the Lawrence Berkeley National Laboratory, at the University of California in Berkeley and in Los Angeles.|
|Years: 1997 to 1998||Country / Region: Switzerland||Summary: The expert was a research assistant in Hoffman-La Roche in Basel|
|Associations / Societies|
|The Biophysical Society|
|Marie-Curie Post-doctoral Fellow;
EMBO Post-doctoral Fellow
|Awards / Recognition|
|Marie-Curie Intra-European Research Fellowship Award;
EMBO Long-Term Research Fellowship Award;
Best PhD Dissertation Award, UCLA Department of Biochemistry;
Keystone Symposia Scholarship;
EMBO Short-Term Fellowship Award;
International Union of Pure and Applied Biophysics Travel Fellowship;
Graduate Award for Excellence in Research UCLA Department of Chemistry and Biochemistry
|Publications and Patents Summary|
|Expert has 22 publications, 1 recent book on nanotechnology, 2 granted patents and 1 patent application|