Expert Details

Expert in Clinical Chemistry, Laboratory Diagnostics, Immunoassay Development, Therapeutic Drug Monitoring

Expert ID: 722043 New York, USA

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Expert has extensive experience in the field of clinical chemistry and clinical diagnostics. Development of analytical methods for trace analytes in biological fluids, especially in the field of clinical diagnostics, has been Expert's main job responsibility and success over the last 15 years. While his primary experience and major contributions lie in the area of developing immunoassay methods, many other biochemical techniques had to be mastered in completing his projects. Protein biochemistry, immunochemistry, electrophoresis, various kinds of purification and chromatographic techniques, organic synthesis, protein purification and conjugation, and determination of purity of biomolecules are all topics he is well-versed in.

Expert has synthesized several dye polymers, conjugated them to analytes like thyroxine, to develop a thyroxine immunoassay. He has so far developed homogeneous or heterogeneous immunoassays, using colorimetric, enzyme, or chemiluminescent labels, and many types of paramagnetic, or otherwise 'beads' for some twenty analytes in clinical diagnostics, including drugs that need therapeutic monitoring. He has many publications in the field and is frequently invited to give seminars in national and international conferences.

Expert has developed commercially sold methods for therapeutic drug monitoring of several cardioactive, antiasthmatic, antiepileptic and antibiotic drugs. He has written some 20 papers, presented more than 30 posters, and given seminars in many national and international conferences on therapeutic drug monitoring in human, drug toxicology and drug-drug interaction.

Expert was a consultant to a company's deoxypyridinoline assay development, when the team faced serious technical issues. He developed methods and assisted the team to investigate why the new assay sometimes gave incorrect clinical results, and showed how it could be fixed.He was asked to consult and assist to company's ACS:180® (Automated Chemiluminescence System) vancomycine assay product. He developed a new way to conjugate the chemiluminescent label to the analyte. The new process reduced process time by 60% and cost by 78%, and made the process more reliable.

Expert may consult nationally and internationally, and is also local to the following cities: Philadelphia, Pennsylvania - Allentown, Pennsylvania - Reading, Pennsylvania - Bethlehem, Pennsylvania - Lancaster, Pennsylvania - Trenton, New Jersey - Camden, New Jersey - Wilmington, Delaware - Baltimore, Maryland - Alexandria, Virginia

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Education

Year Degree Subject Institution
Year: 1983 Degree: Ph.D. Subject: Bio-Organic Chemistry Institution: Yale University
Year: 1978 Degree: M.Phil. Subject: Biochemistry Institution: Yale University
Year: 1977 Degree: M.S. Subject: Biochemistry Institution: Yale University
Year: 1975 Degree: M.S. Subject: Organic Chemistry Institution: Indian Institute of Technology
Year: 1973 Degree: B.S. Subject: Chemistry Institution: Calcutta University

Work History

Years Employer Title Department Responsibilities
Years: 1992 to Present Employer: Undisclosed Title: Manager, Assay Development Department: Diagnostics Responsibilities: Expert is manager of (Undisclosed)'s assay development for their automated chemiluminescent immunoassay systems.
Years: 1989 to 1992 Employer: Cirrus Diagnostics Title: Senior Scientist Department: Responsibilities: Expert was engaged in the development of and regulatory filing for immunoassays for the automated IMMULITE analyzer.
Years: 1984 to 1989 Employer: Photest Diagnostics Title: Scientist Department: Responsibilities: He researched the synthesis and conjugation of chromogenic polymers to biomolecules, and also worked on immunoassay development.
Years: 1983 to 1984 Employer: University of Texas Title: Postdoctoral Fellow Department: Department of Pathology Responsibilities: Expert’s postdoc work at the Univ. of Texas consisted of research in clinical diagnostics. Additionally, he acted as Assistant Director of Clinical Chemistry.

Career Accomplishments

Associations / Societies
Expert is a member of the American Association of Clinical Chemistry (AACC), the International Federation of Clinical Chemistry, the International Association of Therapeutic Drug Monitoring, and the Clinical Ligand Assay Society (CLAS).
Licenses / Certifications
He has the distinction of receiving the highest certification in clinical chemistry – Expert is a certified Diplomate from the American Board of Clinical Chemistry (ABCC) in Washington, D.C.
Professional Appointments
He is on the Editorial Board for the AACC’s bimonthly Therapeutic Drug Monitoring (Ther Drug Monit), and is an Edit Reviewer for Life Sciences, the Journal of Immunochem. Research, and AACC National Meeting Abstracts.
Awards / Recognition
Expert has received numerous awards and merits for his work. He won Best Speaker Award at the AACC National Meeting, San Francisco, and the Clinical Chemistry Recognition Award from the association. He was the recipient of a Quality Recognition Award. During his graduate studies at Yale University, Expert obtained the highest GPA (4.0 equivalent) and a Merit Fellowship from the school. Prior to this, he was National Science Talent Scholar, Government of India, and National Scholar, Government of India (based on top scorer in National Merit Test, Government of India).
Publications and Patents Summary
He has 38 papers, 46 abstracts, and four patents in the field of analytical chemistry, clinical chemistry, immunoassay development, and therapeutic drug monitoring-clinical toxicology.

Additional Experience

Training / Seminars
Expert has delivered many presentations during his professional career. He presented a workshop on assay interference at the National Meetings of the American Association of Clinical Chemistry. He also presented roundtables on various topics in clinical diagnostics at: the National Meetings of the AACC the International Federation of Clinical Chemistry in Florence, the International Congress of Clinical Chemistry in London, and the International Conference of Therapeutic Drug Monitoring in Vienna.
Vendor Selection
He has much experience with HPLC, having set up high performance liquid chromatography systems at his employers. This involved screening and choosing a vendor, arranging set-up and supervising instrument use.

Language Skills

Language Proficiency
German Expert reads and writes German well. The language was a graduate school requirement, used in perusing scientific literature.
Hindi He learned Hindi in school in India.
Bengali Expert is highly proficient in Bengali, his mother tongue.

Fields of Expertise

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