Expert in Computational Biology: Antibody Modeling, Antibody-Antigen Interaction, Protein Structure Prediction
Expert may consult nationally and internationally, and is also local to the following cities: Boston, Massachusetts - Worcester, Massachusetts - Springfield, Massachusetts - Lowell, Massachusetts - Cambridge, Massachusetts - Brockton, Massachusetts - New Bedford, Massachusetts - Hartford, Connecticut - Manchester, New Hampshire - Providence, Rhode Island
|Year: 2010||Degree: PhD||Subject: Chemical & Biomolecular Engineering||Institution: Johns Hopkins University|
|Year: 2004||Degree: M. Tech||Subject: Biotechnology and Biochemical Engineering||Institution: Indian Institute of Technology (IIT) Kharagpur|
|Year: 2004||Degree: B. Tech||Subject: Biotechnology and Biochemical Engineering||Institution: Indian Institute of Technology (IIT) Kharagpur|
|Years: 2010 to Present||Employer: Undisclosed||Title: Post Doc: Computational Scientist: Antibody Design||Department: Protein Engineering & Antibody Technology||Responsibilities: Develop novel strategies for increasing antibody efficacy.|
|Years: 2004 to 2010||Employer: Johns Hopkins University||Title: Graduate Research Assistant||Department: Chemical & Biomolecular Engg||Responsibilities: Developed antibody homology modeling algorithms: RosettaAntibody (http://antibody.graylab.jhu.edu), protocol for backbone flexible antibody-antigen interaction complex prediction: SnugDock|
|Years: 2003 to 2003||Employer: University of Cambridge||Title: Summer Intern||Department: Biochemistry||Responsibilities: Project: Structural assignment for the Drosophila genome and mapping of known mutations
The work comprised of bioinformatics involving high throughput modeling and automatic analysis of results to generate useful statistics. The programming was mainly carried out in Perl and Python, with MySQL being used to store the data.
|Years: 2002 to 2002||Employer: National Center for Biological Sciences (NCBS)||Title: Summer Intern||Department:||Responsibilities: Project: Delving Deep into Deep Orange and Carnation from a Computational Viewpoint
The work involved modeling (using MODELLER) of the two Drosophila proteins Deep Orange and Carnation and finally docking them to find out the interacting regions (using GRAMM).
|Years: 2001 to 2001||Employer: Tata Institute of Fundamental Research (TIFR)||Title: Visiting Summer Research Program Student||Department: Biological Sciences||Responsibilities: Projects:
1) An attempt to find genes responsible for synaptic transmission using Drosophila melanogaster as a model system.
The work involved extensive Fly Pushing and screening flies for phototactic and paralytic defects.
2) Effect of Conus toxins on Drosophila melanogaster
|Associations / Societies|
|Sigma Xi, ACS, AIChE, Biophysical Society|
|Awards / Recognition|
|Rob Roy Fellowship|
|Publications and Patents Summary|
|He has been invited to write a book chapter on antiody modeling to be published in May, 2011. Additionally he has seven international peer-reviewed publications on computational structural bioinformatics with a focus on prediction of structures of antibody and antibody-antigen complexes.|