Expert Details

Expert in Drug Delivery, Drug Development, Business Development, IP Strategy, Medical Nanotechnology,

Expert ID: 723808 North Carolina, USA

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As a business development exectuive and as CEO of several life sciences companies, he has had the opportunity to be closely involved and lead the identification, negotiation and closing of a number of licensing and R&D agreements with pharmaceutical, biotechnology, and government entities. In aggregate over his 20 years in life science businesses, he has closed on more than $500 million in R&D funding and licensing fees. Throrough knowledge of intellectual property adds an important dimension to constructing effective deals.

He has been closely involved in controlled and sustained release technology in several instances, having developed and out-licensed two products that reached the market (Gliadel for brain tumors) and Skedaddle (topical repellant) and two others (antibiotic and an analgesic) that were out-licensed.

Throught his business career, drug delivery has been a constant focus of expertise and experience. Having managed the development of several medical and consumer products based on drug delivery technology, he has accumulated extensive experience with in-house proprietary technology as well as broad knowledge of competitive approaches. His exposure has included polymer, lipid, and carbohydrate matrices, medicinal chemistry (PEGylation, amphiphillic polymers), crystallization, nasal and lung devices, and most recently, nanotechnology.

Innovation has been at the heart of this expert's career, from his academic research period and throughout his business career. Passion for the interface between science and making products that can be commercialized has been a key motivator for his long interest in early-stage company innovation and product development. The process of innovation is of crucial importance to the efficient conversion of science into useful technology and must be tightly coupled to understanding of and proper utilization of intellectual property protection.

The emergence of nano-scale technology for developing new solutions to deliver bioactive compounds into the body and then to selected tissues (and away from tissues) is redrawing the drug delivery and drug formulation sectors. The structural instability, high cost of goods, and side effect potential of modern drug classes (e.g., polyamino acids, nucleic acids) require new, engineered approaches to deliver bioactive substances to targets. He has been closely involved in this field, both developing specific nanotechnology and cultivating expertise in the competitive arena.

Array

He has participated in several half-day consulting sessions on topics in drug delivery strategy and tactics, engaged by companies directly or through consulting firms who engaged me as a participant in a multi-consultant session.He performed several on-site consulting engagements over a 6 month period in 1987 with Boston companies entering life-sciences markets and seeking expert advice on biotechnology product pre-clinical development and on adapting a chemistry manufacturing software program for protein manufacturing.

Expert may consult nationally and internationally, and is also local to the following cities: Raleigh, North Carolina - Greensboro, North Carolina - Durham, North Carolina - Winston Salem, North Carolina - Fayetteville, North Carolina - Cary, North Carolina - High Point, North Carolina - Greenville, North Carolina - Concord, North Carolina - Lynchburg, Virginia

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Education

Year Degree Subject Institution
Year: 1987 Degree: MBA Subject: Management of Technology Institution: MIT
Year: 1976 Degree: PhD Subject: Biology Institution: Syracuse University
Year: 1968 Degree: BS Subject: Biology, Chemistry Institution: University of Pittsburgh

Work History

Years Employer Title Department Responsibilities
Years: 2006 to 2007 Employer: Liquidia Technologies Title: Leader, Biotechnology and Pharmaceuticals Department: Responsibilities: Part-time position: Strategy, planning and execution of therapeutic product sector for a nanotechnology manufacturing platform
Years: 2005 to 2006 Employer: Wake Forest University Title: Executive VP Department: Health Sciences Responsibilities: Directed development of a research park.
Years: 1992 to 2005 Employer: Nobex Corporation Title: CEO, President and Director Department: Responsibilities: General management, capital raising, product development, business development, intellectual property. Company sold in 2006 to Biocon
Years: 1994 to 1998 Employer: Larex International Title: CEO, President and Director Department: Responsibilities: General management, capital raising, manufacturing, product development, business development, intellectual property. Company sold in 2006 to Lonza
Years: 1993 to 1994 Employer: Medical Innovation Partners Title: Principal Department: Responsibilities: Entrepreneur-in-Residence. reviewed business plans, performed due diligence, business development. Left to join MIP-funded Larex.
Years: 1987 to 1992 Employer: Nobex Pharmaceutical Title: VP Business Development Department: Responsibilities: Member of Management Committee, P&L responsibility for two divisions, NovaScreen (pharmacology services) and drug delivery, business development in Japan and EU. Company sold to Scios (division of J&J) in 1992
Years: 1979 to 1987 Employer: Boston University Title: Assistant Professor Department: Biology Responsibilities: NIH supported research and teaching in neurobiology and Director of Graduate Studies.
Years: 1968 to 1972 Employer: US Navy Title: Lieutenant Department: Special Warfare Group Responsibilities: Line Officer serving in SE Asia and Japan

Government Experience

Years Agency Role Description
Years: 1988 to 1991 Agency: NIH Role: Principle Investigator Description: Led mulit-year, several million dollar contract for receptor binding screening of bioactive molecules for the National Institute of Mental Health

International Experience

Years Country / Region Summary
Years: 2004 to 2005 Country / Region: Malaysia and Singapore Summary: He made four trips of 2-3 days each to explore potential new business opportunities for the company he was CEO of and as a member of a scientific advisory board for another, Malaysia-based
company. For the latter company, we successfully established a start-up company in Malaysia, operated by local staff, and continue to develop product opportunities. He
maintains a network of contacts in Kuala Lumpur.
Years: 2003 to 2005 Country / Region: India Summary: During a three year period, he made 6 trips to Bangalore, India to establish and operate a
strategic alliance with India's largest biotechnology company. Three product licensing agreements and related equity investments were completed. Also toured and held discussions with several Bangalore area companies specializing in preclinical and clinical studies as well as product manufacturers.
Years: 2000 to 2005 Country / Region: Taiwan Summary: As CEO of a biotechnology company, he made 8 trips to Taipei to raise equity investments (closed on >$10 million) and to establish alliances with Taiwan based biotechnology and pharmaceutical companies. He maintains a network of contacts in Taiwan.
Years: 1988 to 2005 Country / Region: Japan Summary: While in the US Navy, he lived in Japan for 7 months. As VP for Business Development for a biotechnology company, he was responsible for Japan, traveling to Japan an average of 2 times per year for 6 years to close service contracts and form strategic alliances with Japanese pharmaceutical companies.
Years: 1988 to 2005 Country / Region: Europe Summary: As VP for business development for one firm and CEO for two others, he travelled at least 3 times per year over 7 years to various EU countries, primarily UK, France, Germany, Sweden, and Switzerland. Several strategic alliances for drug product development in the pharmaceutical industry were established and run for multiple years. In addition, he raised equity investment ($>5 million) from EU venture capital groups and attended several biotechnology conferences to present his companies. He has traveled to Israel twice to work with Israeli university researchers for whom his companies sponsored product development research. He
maintains a large network of contacts across the EU in pharmaceutical and biotechnology.

Career Accomplishments

Associations / Societies
He is a member of the Licensing Executives Society, The Association for Corporate Growth, Controlled Release Society, and the Society for Neuroscience
Professional Appointments
He is Chairman of the Board for one early stage company and is a Director of 2 other entrepreneurial companies in the life sciences
Awards / Recognition
He has several medals from his period in the US Navy
Publications and Patents Summary
He has 34 issued and pending patents in the US (>350 related patents issued or filed in foreign countries). He has 28 peer-reviewed papers (1976 - 2002) and is co-author on a book on Global Patent Strategy to be published in 2007.

Additional Experience

Training / Seminars
He has led many scientific seminars in neurobiology and pharmacology during his professorship period. He has served on several invited panels on intellectual property at national conferences. He has been invited to speak in seminars and on panels on the topic of entrepreneurialism in life sciences.
Vendor Selection
Managed staff who did so.
Marketing Experience
Extensive marketing of pharmacology services to pharmaceutical companies. Marketing (business development) of technology of biotechnology companies to pharmaceutical companies. Key executive in bringing 4 therapeutic products into human clinical studies; to date, one has reached market. Key executive in developing consumer dermal product that reach market.
Other Relevant Experience
Inventor (34 US patents issued and pending); Director on several early stage company boards; scientific writer

Language Skills

Language Proficiency
English Native language

Fields of Expertise

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