Expert Details

Expert in Epidemiology, Pediatrics, Infectious Diseases, HIV/AIDS, Immunology, Public Health

Expert ID: 722575 Oregon, USA

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In her various positions at the Centers for Disease Control and Prevention, Expert has dealt with the ethical issues surrounding policy decisions involved in hemophilia-AIDS, transfusion-associated AIDS, AIDS in developing countries, AIDS prevention, child abuse, and child homicide prevention. She has served as a member of the CDC IRB Committee and on safety monitoring committees for NIH clinical trials.

Expert has done extensive research concerning a wide variety of biomedical topics, including prognostic markers, pathogenesis, immune correlates and therapy of HIV, AIDS, Kawasaki Disease, various bacterial, viral, and parasitic infections, and sepsis/bloodstream infections. These are reflected in her numerous publications on these topics.

Expert has done extensive research concerning the T-cell antigen receptor, superantigens, cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection.

Expert has numerous publications in which she has used four-color, six-parameter flow cytometry to examine cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection. She is a world's expert in using a flow cytometric approach to examining these issues, as evidenced by her numerous publications in peer-reviewed journals.

Expert has published extensively on primary and secondary immunodeficiency. She trained with Dr. Erwin Gelfand and Expert. Janeway Senior and Junior. Expert has been on the Emory University faculty, caring for patients, training Fellows, and doing research concerning clinical immunologic issues for the past 23 years.

Expert graduated from Harvard Medical School, did her residency at the Children's Hospital of Los Angeles, and completed an immunology fellowship at Hospital for Sick Children, Toronto. She was on faculty at Yale University of Medicine prior to moving to Atlanta, where she has been on the clinical faculty of Emory University School of Medicine for 23 years, attending in and teaching pediatrics, immunology, and infectious diseases. Expert has provided advice, consultation, and lectures to numerous universities, hospitals, organizations, and ministries of health.

Expert was responsible for the design, execution, and analysis of the epidemiologic and immunologic components of several multicenter studies concerning hemophilia-associated AIDS. She was responsible for the design of these protocols, as well as for their submission to and clearance through numerous Institutional Review Boards and advisory groups. These studies were done in collaboration with the National Institute of Health, a large number of universities, and medical treatment facilities. Their nature and productivity are reflected in numerous publications in peer-reviewed journals.

Expert has designed and managed numerous clinical research studies, most notably in the area of hemophilia-associated AIDS. She has been responsible for protocol design, study coordination, data analysis, and preparation of manuscripts submitted and accepted by peer-reviewed journals. These skills are reflected in her numerous publications. For the above-mentioned studies, Expert was the primary contact person for coordination with universities, health institutions, and federal agencies. She was responsible for clearance of protocols through Institutional Review Boards and for updating these Boards and Institutions about study activities. Expert supervised data collection,management, and analysis. She dealt with problems at the patient, practitional, and institutional levels. Her skill at successfully managing clinical research studies are reflected in her numerous publications.

Expert is a world expert in evaluation of cell-specific cytokines in humans. She has evaluated and published primary research on the cytokine network in healthy individuals at various ages and also in a wide variety of disease states, including sepsis, bloodstream infections, HIV infection, malaria, and malnutrition.

Expert has published primary research concerning a number of diseases, including but not limited to HIV infection, HTLV, Kawasaki disease, bloodstream infections, malaria, parvovirus infection, Kaposi sarcoma, malnutrition, and vitamin A deficiency.

Expert is currently in the process of preparing two books for the layperson concerning the problems of adolescents, one book directed at parents and one, directed at the adolescent. One chapter of each of these book deals with eating disorders, including bulimia nervosa, anorexia nervosa, binge eating, purging, and obesity.

Expert spent 23 years at the Centers for Disease Control and Prevention, performing research and assisting in policy making concerning health management issues, especially in the areas of child health, infectious disease prevention, and sexually transmitted diseases. In addition, she has published a parenting book for the layperson concerning management of the health of premature infants. This parenting book was published in hardback by Henry Holt, Inc., and in paperback by Doubleday Dell, Inc. She is currently working on two books for the layperson concerning adolescent health.

Expert has numerous publications in which she has used four-color, six-parameter flow cytometry to examine cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection. She is a world's expert in using a flow cytometric approach to examining these issues, as evidenced by her numerous publications in peer-reviewed journals. She has also examined the roles of nutrition, vitamin A, and BCG vaccination on host resistance to infection.

Expert has published several papers that examine the relationships between cellular and humoral immunity in a variety of disease states, including HIV, HSV, and Kaposi sarcoma.

Expert trained with Dr. Erwin Gelfand and Expert. Janeway Senior and Junior, did immunobiologic research at Yale University, and did research on immunobiologic issues at the Centers for Disease Control and Prevention for the past 23 years. Her research and publications concern the T-cell antigen receptor, superantigens, cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection.

Expert graduated from Harvard Medical School, did her residency at the Children's Hospital of Los Angeles, and completed an Immunology fellowship at Hospital for Sick Children, Toronto. She trained with Dr. Erwin Gelfand and Expert. Janeway Senior and Junior. She was on faculty at Yale University of Medicine, doing basic immunologic research, prior to moving to Atlanta, where she has been on the clinical faculty of Emory University School of Medicine for 23 years, attending in and teaching pediatrics, immunology, and infectious diseases. Expert has numerous research publications concerning the T-cell antigen receptor, superantigens, cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection.

Expert has clinical expertise managing and extensive research experience/publications concerning immunosuppression related to retroviral and other infections, malnutrition, and chemotherapy. Expert has been on the Emory University faculty, caring for patients, training Fellows, and doing research concerning clinical immunologic issues for the past 23 years.

Expert has done research on and has a number of papers in peer-reviewed journals concerning the role of interferon-gamma in HIV infection and bloodstream infections. She has also published concerning the relationships between cell-specific interferon-gamma production and the clinical course/outcome of various infections, as well as vitamin deficiencies and malnutrition.

Expert has numerous publications in which she has used four-color, six-parameter flow cytometry to examine cell-specific cytokines, T-cell subsets, immunoregulatory cells, the cytokine network, and innate immunity, both in relation to and independent of HIV infection. In particular, she has examined the relationships between cellular and serum IL-2, 4, 5, 6, 8, and 10, as well as the role of these cytokines in a variety of pathologic states. She is a world's expert in using a flow cytometric approach to examining these issues, and comparing various approaches to measuring interleukins, as evidenced by her numerous publications in peer-reviewed journals.

Expert has done extensive research concerning the T-cell antigen receptor, superantigens, and the cytokine network, both in relation to and independent of HIV infection. She has examined the roles of various HIV molecules in HIV disease pathogenesis of HIV.

Expert graduated from Harvard Medical School, did her residency at the Children's Hospital of Los Angeles, and completed an Immunology fellowship at Hospital for Sick Children, Toronto. She was on faculty at Yale University of Medicine prior to moving to Atlanta, where she has been on the clinical faculty of Emory University School of Medicine for 23 years, attending in and teaching pediatrics, immunology, and infectious diseases. Expert has done research concerning and published in the areas of: child health, breastfeeding, prematurity, infant mortality, child abuse, pediatric and hemophilia-related HIV infection/AIDS, Kawasaki disease, pediatrician/patient/parent communication, and parenting. Expert has provided advice, consultation, and lectures to numerous universities, hospitals, organizations, and ministries of health concerning pediatric issues.

Expert trained in epidemiology and public health at the Centers for Disease Control and Prevention, in (CDC)'s Epidemiology Intelligence Service (EIS) and Preventive Medicine Residency Program. She was an adjunct associate professor at the Rollins School of Public Health at Emory University for nine years and, as a respected medical epidemiologist, chaired and/or was a member of numerous committees, including CDC's EIS Course Survey Committee, CDC's EIS Conference Planning Committee, CDC's Medical the Advisory Board, CDC's Institutional Review Board, the Public Health Service (PHS)'s Promotion Board, National Institute of Health (NIH)'s Data and Safety Monitoring Board for the Clinical Trial of Intravenous Gammaglobulin in HIV-Infected Children, and the National Collaborative Hemophilia Growth & Development Study Executive Committee. Expert held a number of positions at CDC, including as a Medical Epidemiologist in the Office of the Director, Center for Health Promotion and Education; Chief of the Epidemiology Studies Section in the Division of Host Factors, Center for Infectious Diseases (CID); Chief of Applied Communications Research, Epidemiology & Evaluation, National AIDS Information and Education Program; and Chief of the Immunoregulatory Laboratory, NCID. Expert has supervised outbreaks involving infectious diseases, blood product contamination, and violence. She designed, supervised, analyzed, and reviewed numerous epidemiologic and clinical outbreaks and studies and supervised CDC's Hemophilia-Associated AIDS Surveillance System. Expert has a unique combination of epidemiologic, clinical, and basic laboratory training and experience. She has been involved in numerous peer-reviewed publications, Morbidity and Mortality Weekly Reports, and PHS recommendations on areas ranging from child health, HIV, blood product safety, infectious diseases, immunodeficiency, to violence.

Expert has designed, supervised, analyzed, and reviewed numerous epidemiologic and clinical outbreaks and studies.

Expert trained in epidemiology and public health at the Centers for Disease Control and Prevention, in (CDC)'s Epidemiology Intelligence Service (EIS) and Preventive Medicine Residency Program. She was an adjunct associate professor at the Rollins School of Public Health at Emory University for nine years and, as a respected medical epidemiologist, chaired and/or was a member of numerous committees, including CDC's EIS Course Survey Committee, CDC's EIS Conference Planning Committee, CDC's Medical the Advisory Board, CDC's Institutional Review Board, the Public Health Service (PHS)'s Promotion Board, National Institute of Health (NIH)'s Data and Safety Monitoring Board for the Clinical Trial of Intravenous Gammaglobulin in HIV-Infected Children, and the National Collaborative Hemophilia Growth & Development Study Executive Committee. Expert held a number of positions at CDC, including as a Medical Epidemiologist in the Office of the Director, Center for Health Promotion and Education; Chief of the Epidemiology Studies Section in the Division of Host Factors, Center for Infectious Diseases (CID); Chief of Applied Communications Research, Epidemiology & Evaluation, National AIDS Information and Education Program; and Chief of the Immunoregulatory Laboratory, NCID.

Array

Consulted with the Armenian government concerning their newborn care network at the request of Harvard University.Reviewed clinical charts to advise lawyers involved in a wide variety of litigation, including but not limited to disability, personal injury, wrongful death, breach of contract, fraud, and malpractice litigation.Lectured at numerous universities in a variety of countries concerning her areas of expertise.She has been a member of the Public Health Service promotion board. Expert has been a member of CDC's Institutional Review Board.

Expert may consult nationally and internationally, and is also local to the following cities: Medford, Oregon

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Education

Year Degree Subject Institution
Year: 1975 Degree: M.D. Subject: Medicine Institution: Harvard Medical School
Year: 1971 Degree: B.A. Subject: Biology Institution: University of Chicago

Work History

Years Employer Title Department Responsibilities
Years: 2003 to Present Employer: Undisclosed Title: CEO Department: Responsibilities: CEO of a medical consulting firm.
Years: 1992 to 2003 Employer: National Center for Infectious Diseases, Centers for Disease Control and Prevention Title: Director, Immunoregulatory Laboratory Department: HIV Immunology Branch, Div. of AIDS, STD, & Tuberculosis Laboratory Research Responsibilities: She conducted research and supervised research by others.
Years: 1982 to Present Employer: Undisclosed Title: Attending Faculty Department: Pediatric Immunology, Infectious Diseases, & Epidemiology Responsibilities: Teaches, does medical consulting, and provides patient care.
Years: 1989 to 1992 Employer: Centers for Disease Control Title: Chief, AIDS Communications Research Department: OD (HIV) Responsibilities: She was in charge of the group that did research concerning AIDS communications and evaluated the effectiveness of the National AIDS Media Campaign.
Years: 1983 to 1989 Employer: Division of Host Factors, Center for Infectious Diseases, Centers for Disease Control Title: Chief, Hemophilia AIDS Research & Surveillance Department: Division of Host Factors Responsibilities: Was responsible for supervising all CDC's hemophilia-associated AIDS epidemiologic activities.
Years: 1982 to 1983 Employer: , Center for Health Promotion and Education, Centers for Disease Control Title: Medical Officer Department: OD, Center for Health Communications Responsibilities: She did research that helped found CDC's Center for Injury Control and Prevention. Her research was ground-breaking in the areas of child abuse and homicide.
Years: 1980 to 1982 Employer: Division of Family Planning, Centers for Disease Control Title: EIS Officer Department: Epidemiology Intelligence Service (EIS) Responsibilities: Initiated her work at CDC through joining the world-renowned EIS Program, a training program in epidemiology, public health, and preventive medicine.
Years: 1978 to 1980 Employer: Howard Hughes Medical Institute, Yale University School of Medicine Title: Research Associate Department: Immunology/Immunopathology Responsibilities: She performed bench research on T-cell immunology and immunoregulation.

Government Experience

Years Agency Role Description
Years: 1987 to 1987 Agency: CDC Role: Chairman, Epidemiology Intelligence Service Conference Planning Committee Description:
Years: 1988 to 1990 Agency: CDC Role: Medical Advisory Board Description:
Years: 1989 to 1991 Agency: NIH Role: Member, Data and Safety Monitoring Board Description: Monitored the NIH trial of intravenous gammaglobulin for HIV-infected children.
Years: 1986 to 1996 Agency: CDC & NIH Role: Hemophilia Growth & Development Study Description: She was a member of the Executive Committee from l986-1995. She was Chairman of the Immunology Subcommittee from 1986-1991. She was a member of the Publications Committee from 1987-1996.

International Experience

Years Country / Region Summary
Years: 1990 to 1990 Country / Region: Armenia Summary: Advised the Armenian government on organizing its neonatal transport and medical facilities and activities.
Years: 1997 to 1999 Country / Region: Thailand Summary: Collaborated in studies done with the Ministry of Health concerning the immunology and pathogenesis of HIV/AIDS.
Years: 1997 to 2003 Country / Region: Malawi, Africa Summary: Collaborated in studies done with the Ministry of Health concerning the immunology and pathogenesis of HIV/AIDS.
Years: 2000 to 2003 Country / Region: Mozambique, Africa Summary: Collaborated in studies done with the Ministry of Health concerning the immunology and pathogenesis of HIV/AIDS.

Career Accomplishments

Associations / Societies
Expert is a world-renowned expert in the areas of immunology, HIV/AIDS, child health, and health communications. She is a member of: Society for Pediatric Research; American Association of Immunologists; American Federation for Clinical Research; American Society for Microbiology; Pediatric Infectious Disease Society; Sigma Xi, The Scientific Research Society; Clinical Immunology Society; and Phi Beta Kappa.
Licenses / Certifications
She holds a medical license (M.D.) and is board-certified in pediatrics (F.A.A.P.).
Professional Appointments
Expert was a Research Associate at the Yale University School of Medicine and is an Associate Professor at the Emory University School of Medicine.
Awards / Recognition
She is a Fellow of the Infectious Disease Society of America, and is a Scientific Fellow, American College of Allergy and Immunology.
Expert's other honors include: Trustee Scholar; L. G. Selz Scholarship; Phi Beta Kappa Honor Society; Graduated with highest honors; Department of Health and Human Services Public Health Service Group Award to the "Infant Feeding Task Force,"; Public Health Service (PHS) Commendation Medal, November; PHS Outstanding Unit Citation; PHS Commendation Medals (three); American Society of Microbiology Lectureship
Medical / Professional
She did her pediatric internship and residency at the Los Angeles Children's Hospital. She had an immunology and allergy fellowship at the Hospital for Sick Children, Toronto, Ontario, Canada. She had an epidemiology fellowship with the Epidemiology Intelligence Service, CDC.
Publications and Patents Summary
Expert has over 100 scientific, peer-reviewed publications to her credit and has authored a parenting book for the layperson. This book was published by Henry Holt (hardback) and Doubleday Dell (paperback).

Additional Experience

Expert Witness Experience
Since 2003, Expert has reviewed numerous medical cases as an expert consultant in epidemiology, infectious diseases,general medicine, immunology, and/or pediatrics,. She has provided opinions in legal cases and produced supporting reports, statements, and affidavits. She has provided written rebuttals of other experts's report, participated in depositions, and testified at trials.
Training / Seminars
She has given numerous lectures and participated in college and graduate level teaching in her areas of expertise.
Other Relevant Experience
Expert has designed and analyzed numerous epidemiologic and clinical studies and also advised in these areas. At the request of various clients, she has performed epidemiologic studies for corporate clients and provided the results to various entities, including legislative bodies.

Fields of Expertise

AIDS, cellular immunity, cellular immunology, clinical immunology, clinical medicine, clinical protocol, clinical research, clinical research management, clinical study, cytokine, disease, eating disorder, health care management, host resistance, humoral immunology, immunology, immunosuppression, interferon, interleukin, human immunodeficiency virus, pediatrics, epidemiology, Methicillin-resistant Staphylococcus aureus, medical statistics, public health, pediatric immunology, medical causation, bacterial disease, blood borne disease, central nervous system infection, disease control, disease outbreaks, immunization, immunodeficiency, immunosuppressive drug, infection, infection control, infection prevention, infectious disease, infectious disease control, infectious disease diagnosis, infectious disease transmission, infectious disease treatment, meningitis, microbial control, nosocomial infection, osteomyelitis, pediatric infectious disease, pneumocystis carinii pneumonia, preclinical research, prevention, preventive medicine, septicemia, vaccination, hospital epidemiology, gram-negative bacterial infection, E. coli infection, herpes virus infection, lice infestation, AIDS dementia complex, pharmacoepidemiology, child molestation, sinus infection, fever, genital wart, Perinatology, nutrition disorder, strategic market planning, consumer survey, clinical measurement, beta interferon, Pseudomonas aeruginosa, blood sampling, clinical laboratory, health care industry quality management, cryptosporidiosis, bulimia co-morbidity, immunodiagnostics, legionellosis, molecular immunology, clinical virology, autoimmune disease, biological response modifier, botulism, home health care, infectious cardiovascular disease, infectious urinary system disease, infectious reproductive system disease, infectious lymphatic system disease, hepatitis, candidiasis, vaccine, yaws, virology, therapy, syphilis, strongyloidiasis, sporotrichosis, serology, schistosomiasis, scabies, rickettsial disease, rabies, pneumonia, parasitic disease, molecular biology, measles, malaria, Lyme disease, leptospirosis, impetigo, immunoglobulin, immunoassay, health care system, mycosis, empyema, diagnostics, cytotoxic T lymphocyte, chronic disease epidemiology, chickenpox, biostatistics, bacterial pneumonia, aspergillosis, antigen-antibody interaction, antibody

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