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Expert has spent over 15 years working in the field of analytical chemistry of various labile organic compounds and macromolecules. He worked on the quantitative and qualitative analysis of highly involatile species that required special sample preparation and processing. These species consisted energetic molecules such as nitrosamines that were used in high explosives. His mission is now to focus on the wealth of data that is being either analyzed on premises or in the cloud. Enterprise companies that were developing new product offerings and leveraging this explosion in the data benefited from his contribution.

Expert has sourced and selected special analytical instrumentation that could identify and detect threat substances at the picogram/ liter level in the chemical laboratory as part of a staff of research scientists. He worked on all stages of laboratory equipment certification from the initial installation to the final performance qualification of various instruments ranging from an atmospheric pressure ionization triple quadropole mass spectrometer to a confocal scanning Raman imaging spectromter. He developed new hyphenated analytical techniques and laboratory protocols to analyze molecules such as nitroaromatics in the gas phase and microparticle plastic explosive residues in the condensed phase. Certain of these laboratory techniques such as ion mobility spectrometry were eventually simplified and reduced to compact field analytical instrumentation for deployment by a government agency.

He has also worked on the development of new detection methods, miniaturized analysis modules and chemical sensors for automated real time analysis of a wider array of organic substances. He contributed his instrument design expertise to new detector research by developing standard calibration sources and conducting performance testing to determine figures of merit such as specificity and sensitivity. He determined explosives detection reliability through the generation of receiver operator curves for sensors such as surface acoustic wave resonators and detector modules such as cavity ringdown laser absorption spectrometers. He contributed the engineering design requirements to the final product development of a large volume air sampling concentrator and ion mobility spectrometer that is currently being marketed.

He has modified various optical components such as lasers, monochromators, and CCD cameras to meet subsystem manufacturer specifications . He performed the systems integration to incorporate these components with other detectors that would produce first stage prototypes. One such project involved the design and development of a mid infrared difference frequency laser source for the miniature cavity ringdown cell and concentrator being developed in a joint effort by a major instrumentation company and a university research group. Another project focused on the design of an inlet desorption sampler for a laser photoionization time of flight mass spectrometer.

He has conducted liquid phase spectroscopic studies using colloidal microparticles and polyelectrolytes for probing physical chemical interactions with other target molecules. He worked with molecules such as fluorone dyes for microparticle fluorescence enhancement and nucleic acids for fluorescence resonance energy transfer using both custom laser spectrofluorometers and commercial filter fluorometers. He developed biosensing techniques for oligonucleotide hybridization using aqueous fluorene conjugated polymers that formed the basis for microarray applications. He characterized the sorption process of dilute analytes such as trinitrotoluene down at the microscopic level using techniques such as surface enhanced Raman Spectroscopy.

Expert has applied his analytical expertise towards determining the composition of more complex fluids, gels and dispersions. Recently he has developed protocols for the process analysis of copolymer blends that incorporated polymer derivatives of polyethylene glycol and polydimethylsiloxane using attenuated total reflectance sampling and Fourier Transform Infrared Spectrocscopy. He monitored emulsification processes in-situ using laser scattering spectroscopy. He quantitatively analyzed suspensions, slurries and liquid mixtures of potentially unstable oxidizing compounds such as perchlorates using confocal near IR Raman probing techniques.

He received a request for a quick analytical screening technique to detect natural products such as steroids in a complex binder matrix. He visited the client's laboratory and utilized their existing equipment to come up with an appropriate analytical method. He identified Attentuated Total Reflectance IR Spectroscopy of powdered solids as a quick method to substantiate the presence of the active substance, oxandralone, in generic pharmaceuticals. He wrote a standard operating procedure for the method, and developed a validation protocol to test the technique.