Expert Details

Expert in Laboratory Medicine, Pathology

Expert ID: 107820 Kentucky, USA

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Expert is experienced in the application of basic sciences to clinical and biomedical problems. Most recently, his interests have centered on infectious diseases, concentrating on pathogen-host interactions and biomaterials with special emphasis on biocompatibility.

Expert's laboratory has recently elucidated the importance of adsorbed host proteins in the inflammatory response to polymeric biomaterials. There is ongoing research into the molecular bases of adverse responses to biomaterials and the synthesis of new biocompatible surfaces for medical devices.

Expert's laboratory has been involved in the development of novel diagnostic test procedures, including one for whooping cough (U.S. Patent). Expert also has developed several new procedures to solve specific biomedical problems. These include the addition of Vitamin C to hemodialysis solutions to prevent chlorine-induced oxidant destruction of red blood cells, the clinical use of iron-binding proteins to suppress hemoglobin-driven bacterial infections (U.S. Patent), the development of a novel technique for the synthesis of immobilized iron chelators (U.S. Patent), and albumin-binding biomaterials (U.S. Patent). Expert has consulted in a variety of areas including diagnostic test development, biomaterials (compatibility and stability), and cellular oxidation and reduction reactions.

Expert's past experience includes work on the pathogenesis of red cell disorders, cell membrane function, and a number of problems concerning biological oxidation and reduction reactions. Expert is also knowledgeable in toxicology, cellular regulation, enzymology, and blood flow.

Expert may consult nationally and internationally, and is also local to the following cities: Indianapolis, Indiana - Evansville, Indiana - Bloomington, Indiana - Lexington, Kentucky - Louisville, Kentucky - Owensboro, Kentucky - Cincinnati, Ohio

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Education

Year Degree Subject Institution
Year: 2001 Degree: M.D. (Honorary) Subject: Medicine Institution: University of Linköping, Linköping, Sweden
Year: 1964 Degree: Ph.D. Subject: Biological Anthropology/Human Genetics Institution: University of Michigan, Ann Arbor
Year: 1966 Degree: M.S. Subject: Biological Anthropology Institution: University of Michigan, Ann Arbor
Year: 1964 Degree: M.A. Subject: Biological Anthropology Institution: University of Florida, Gainesville
Year: 1963 Degree: B.A. Subject: Anthropology/Archeology Institution: Florida State University, Tallahassee

Work History

Years Employer Title Department Responsibilities
Years: 2000 to Present Employer: Undisclosed Title: Professor Department: Department of Medicine Responsibilities:
Years: 1996 to 2000 Employer: Baylor College of Medicine Title: Professor Department: Department of Pediatrics Responsibilities:
Years: 1992 to 1996 Employer: Albany Medical College Title: Director Department: Division of Experimental Pathology Responsibilities:
Years: 1992 to 1996 Employer: Albany Medical College Title: Professor Department: Department of Pathology and Laboratory Medicine Responsibilities:
Years: 1972 to 1992 Employer: University of Minnesota Medical School Title: Director of the Medical Genetics Division (since 1979) and Professor Department: Responsibilities:

Fields of Expertise

biocompatibility, infectious disease, oxygen radical biochemistry, pathology, polymer biocompatibility, applied anthropology, medical diagnostic test, test procedure, pathogenesis, biological oxidation, pathologic process, avitaminosis, inflammatory response, pediatric genetics, pediatric pathology, iron chelating agent, industrial microbicide, bioadhesion, bacteriostatic agent, biocompatible coating material, superoxide dismutase, clinical pathology, molecular pathology, biomedical coating material, albumin, biological antioxidant, oxidation reaction, disease, oxidizing agent environmental effect, iron-deficiency anemia, cellular regulation, laboratory, chelating, chelating agent, biomedical device, antioxidant, cell membrane function, cell membrane, bioimplantable material, infectious systemic disease, biological process, hemoglobin, protein, enzyme, erythrocyte destruction, transition element, toxicology, thromboresistant material, therapy, sickle-cell anemia, chemical reduction, pertussis, pathogen, non-combustive oxygen chemistry, oxygen biochemistry, nutritional anemia, neutrophil, medical polymer, medical device, iron, infection control, implantable device, hematologic disease, granulocyte, exotoxin, erythrocyte, enzymology, bacterial endotoxin, diagnostics, chlorine, cell physiology, blood protein, blood flow, blood cell, biomedical engineering, biology, biocompatible polymer, biocompatible material, bacteriology, bactericide, bacterial disease, artificial erythrocyte, artificial blood, artificial artery

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