Expert in Nutrients Absorption Through GI Tract-Interactions of Natural products of Bioactive Foods on Genomes
He has established in devising a novel drug beta- CGRP that prevent the side effects of COX-2 inhibitors. This provides further support of use of COX-2 inhibitors in cancer and inflammation. His recent studies in dietary bioactive citrus compunds supports the prevention of NSAIDs induced hyperpermeability in intestinal epithelial cells. This is a more crucial step in preventing NSAIDs induced inflammation through dietary intervention.
Expert has done extensive work on mechanism of interactions of natural products on cancer chemotherapy in cell culture and animal models. His expertise in in the interactions of curcumin on breast cancer chemotherapy paves a new way in elucidating the interference of dietary supplements on chemotherapy. There are a lot of dietary supplements and dietary bio-active compounds need to be analyzed to prescribe an effective cancer therapy in future, This needs to analyze the bio-availability of bio-active compounds and genomic interactions of these bio-active molecules. He is an expert of both, He has established a novel noninvasive protocol to study the bio-availability and nutrition absorption in human.
Expert has done extensive research on the mechanism of action of aspirin for the intestinal inflammation.
Biochemical analyses of Madras pavilion Restaurants and advise the methods of nutrient stability at Sugar Land, TX.
A reviewer for the Book: Asian Crops and Human Dietetics by Expert. Usha Palaniswamy,Role of turmeric powder and other natural products from diets for the prevention of seasonal flu viral infections to University of Houston.Noninvasive screening methods for Colon cancer screening using nonmetabolizable FDA approved agent, VA hospital and Baylor College of medicine Houston.Identification of Sucrase and isomaltase deficiency in new born, toddlers and young adults by trade marketed noninvasive methods to Baylor College of Medicine, Houston.Consulting to develop novel cell phone diagnostics using noninvasive methods to CDC.Atlanta.
Expert may consult nationally and internationally, and is also local to the following cities: Houston, Texas - Pasadena, Texas - Beaumont, Texas - College Station, Texas - Baytown, Texas - Bryan, Texas - Sugar Land, Texas - Port Arthur, Texas - Galveston, Texas - Missouri City, Texas
|Year: 1985||Degree: PhD||Subject: Biochemistry||Institution: Madurai Kamaraj University|
|Years: 2002 to Present||Employer: Undisclosed||Title: Associate Professor||Department: STEM||Responsibilities: Teaching Biology and research|
|Years: 2000 to 2002||Employer: University of North Carolina-Chapel Hill||Title: Research Associate||Department: Medicine||Responsibilities: Performing research on Animal Models of breast cancer|
|Years: 1997 to 2000||Employer: University of Washington-Seattle||Title: Senior Research Fellow||Department: Surgery||Responsibilities: Research conducted on Intestinal bile acid transporter gene expression and stem cells|
|Years: 1990 to 1997||Employer: Kings College Hospital, London, UK||Title: Associate Clinical Biochemist||Department: Clinical Biochemistry||Responsibilities: Performing human intestinal permeability studies noninvasively and studying mechanism of NSAIDs induced enteropathy.|
|Years: 1985 to 1990||Employer: PSG Institute of Medical Sciences and Research||Title: Assistant and Associate Professor||Department: Biochemistry||Responsibilities: Teaching Biochemistry for Medical graduate students and research|
|Years||Country / Region||Summary|
|Years: 1977 to 1990||Country / Region: India||Summary: Expert has begun his career at India with the research on Medicinal foods for arthritis and diabetes. He has been awarded a national research gold medal for his clinical research on cotton seed aqueous extracts for diabetes (1979). He also received drug research award for withania somnifera for arthritis 1980.|
|Years: 1990 to 1997||Country / Region: United Kingdom||Summary: Studied the mechanism of actions of the NSAIDs induced intestinal inflammation.Studied the noninvasive technique to monitor the human intestinal absorption and permeability in health and diseases like, cardiac pulmonary bypass patients, liver transplant patients, IBD patients, HIV patients, children and NSIADS induced enteropathy. Helped to develop GI toxic free new pharmaceutical products.|
|Years: 1997 to Present||Country / Region: USA||Summary: Studied intestinal bile acid transporter genes, intestinal stem cells at University of Washington Seattle.Studied the interactions of dietary supplement curcumin on human breast cancer at UNC- Chapel Hill.Studying the interactions of nutrients and chemotherapy for prostate and breast cancer. UH-Victoria.|
|Associations / Societies|
|National Association of Biology Teachers|
|Editor for the multiple books and a paper.|
|Publications and Patents Summary|
|Expert. Expert has 36 publications and 2 books edited|
|Training / Seminars|
|NIH sponsored Inside Cancer workshop conducted for Science teachers|
|All Gym and workout clubs.
All yoga practices
All food industries
all pharmaceutical companies.
Dietary supplements health stores
Fruits and vegetable industries.
Hospitals who cares for different category of patients due to leaky gut syndromes.
Cancer chemotherapy and dietary supplements interactions.
GI inflammation screening by noninvasive technique.
Monitoring the non steroidal anti inflammatory agents users for the early onset of intestinal ulcer screening by noninvasive technique,
Colon cancer screening using FDA approved investigation agents by noninvasive techniques.
|As a researcher Expert.. Expert had participated in the development of preclinical research in order to improve the marketability of their products.
Skills pertained to study the "Effect of Prostaglandins on small intestinal inflammation induced by NSAIDs" Searle, UK (1991-1992).
Skills pertained to study the "Effect of (Alpha -Trinisitol on indomethacin induced small intestinal permeability to 51Cr-EDTA and Calprotectin excretion in faeces". Prestorp Pharma, Sweden (1993-1995).
Skills pertained to study the "Effect of Nabumetone on rat small intestinal mitochondrial function". Smith Kline Beecham USA (1994-1996).
Skills pertained to study the "Effect of Cyclooxygenase-2 inhibitor Nimesulide on pathogenesis of small intestinal inflammation". Helsinn Pharmaceuticals, Switzerland, May-December 1996.
Skills pertained to study the "Present investigation of combination of proteosome inhibitor 341 and Doxil on antitumor activity of BT-474 cells xenograft breast cancer model".Millennium Inc, MA
|Other Relevant Experience|
|Present on going skills and services are provided to Baylor College of Medicine to screen sucrase and isomaltase deficiency children by a noninvasive method and try to correct them with appropriate intervention therapeutics.
Present on going services that include advice the clients with the types of nutrients present in vegetables and fruits and inform the specific drug interactions.
Present on going services include the advising the restaurants about the quality of food preparations and the stability of nutrients for a healthy life style.
Advising personalized diet for all especially the yoga practitioners using their genomic profiles for the healthy extension of life style.