Expert Details
Pharmaceutical Process Research, Development, and Manufacturing
ID: 725712
Pennsylvania, USA
Expert has three patents from research, development and manufacturing of etoposide and etoposide phosphate. He also has extensive experience with platinum anticancer drugs, including cisplatin, carboplatin, and oxaliplatin.
He has 17 years of experience in pharmaceutical process research, development and manufacturing.
He has extensive experience in asymmetric synthesis in both graduate school and industry.
Expert did extensive research on the synthesis of tetrahydrocannabinol. This involved terpene chemistry and the chemistry of cyclopropyl epoxides. Six patents were obtained.
He has 17 years of experience in the pharmaceutical process research, development and manufacturing, including many generics.
He has 30 years experience in various forms of organic chemistry.
Expert is a tenured faculty member at Penn State, where has been teaching since 2009. He has published four articles in The Journal of Chemical Education and given several seminars on pedagogical topics, including an invited talk at an international conference.
Expert has extensive experience with controlled substances, including cannabinoids, opiods, amphetamines, and benzodiazepines
Education
| Year | Degree | Subject | Institution |
|---|---|---|---|
| Year: 1991 | Degree: PhD | Subject: Organic Chemistry | Institution: University of Delaware |
| Year: 1986 | Degree: BS | Subject: Chemistry | Institution: George Washington University |
Work History
| Years | Employer | Title | Department |
|---|---|---|---|
| Years: 2009 to Present | Employer: Undisclosed | Title: Associate Professor of Chemistry | Department: Chemistry |
Responsibilities:Teaching General Chemistry and Organic Chemistry courses at the Schuylkill campus. Performing successful research in heterocyclic chemistry with undergraduate students. |
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| Years | Employer | Title | Department |
| Years: 2009 to 2009 | Employer: Merck and Co. | Title: Senior Research Chemist | Department: Process Research |
Responsibilities:Conducted preclinical pharmaceutical process research and development. |
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| Years | Employer | Title | Department |
| Years: 1997 to 2008 | Employer: Johnson Matthey Pharmaceutical Materials | Title: Principal Scientist | Department: Chemical Process R & D |
Responsibilities:He conducted pharmaceutical process research and development, including GMP scale-up of controlled substances and platinum compounds. He shared management and leadership duties. |
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| Years | Employer | Title | Department |
| Years: 1991 to 1997 | Employer: Bristol-Myers Squibb | Title: Senior Scientist | Department: Process Exploration/Technical Operations |
Responsibilities:He conducted pharmaceutical process research and development. |
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Career Accomplishments
| Associations / Societies |
|---|
| American Chemical Society (Lehigh Valley Local Section), Organic and Chemical Education Chemistry Divisions Phi Lambda Upsilon National Chemistry Honor Society Council on Undergraduate Research, Washington, D.C. International Society of Heterocyclic Chemists |
| Professional Appointments |
|---|
| Session Chair, “Targeted Organic Synthesis,” 2006 ACS Middle Atlantic Regional Meeting, Hershey, PA Session Presider, “New Reactions and Methodologies,” Spring 2013 National American Chemical Society Meeting, New Orleans, LA Session Presider, “Heterocycles and Aromatics,” Spring 2015 National American Chemical Society Meeting, Denver, CO Judge, University of Delaware Silver Symposium for graduate students, Newark, DE. Reviewer for Organic Process Research and Development. Reviewer for The Journal of Organic Chemistry. Reviewer for The Journal of Chemical Education Reviewer for Organic and Biomolecular Chemistry Reviewer for for Organic Preparations and Procedures International. Reviewer for Reaction Chemistry & Engineering Reviewer for the American Chemical Society Petroleum Research Fund Undergraduate Research program. Reviewed one grant proposal. |
| Awards / Recognition |
|---|
| 2016 Penn State Schuylkill Award for Excellence in Research or Creative Accomplishments, Penn State Schuylkill, Schuylkill Haven, PA. 1995 Excellence Award, Bristol-Myers Squibb Co., Syracuse, NY. 1991 Elected to Phi Lambda Upsilon Chemistry Honor Society. 1986 Byrne Thurtell Burns Award for Organic Chemistry, George Washington University, Washington, DC. 1985 Chemical Society of Washington Award for the outstanding junior chemistry major at George Washington University, Washington, DC. |
| Publications and Patents Summary |
|---|
| He has 30 publications in refereed journals and 9 patents. |
Additional Experience
| Training / Seminars |
|---|
| Seminars delivered: 13. 3rd Science Symposium: Innovation of Science, Nanotechnology, Human Health and Environment for a Global Society. Coppin State University, Sep. 18, 2015. 12. National Meeting of the American Chemical Society, Denver, CO, Mar. 25, 2015. 11. 23rd International Conference on Chemical Education, Toronto, Ontario, Canada, July 16, 2014. 10. Penn State Hazleton Faculty Development Day, March 20, 2014. 9. Northeast Regional Meeting of the American Chemical Society, New Haven, CT, Oct. 26, 2013. 8. Middle Atlantic Discovery Chemistry Project, Penn State Berks, May 18, 2013. 7. National Meeting of the American Chemical Society, New Orleans, LA, April 7, 2013. 6. National Meeting of the American Chemical Society, New Orleans, LA, April 7, 2013. 5. John T. and Paige S. Smith Symposium, Penn State York, Nov. 10, 2012. 4. Muhlenberg College, Allentown, PA, February 25, 2011. 3. University of Pennsylvania, Philadelphia, PA, January 2003. 2. South Jersey Section, American Chemical Society, March 2000. 1. Colgate University, Hamilton, NY, 1995. |
| Vendor Selection |
|---|
| He worked with outside contractors and vendors who manufactured raw materials and intermediates for JM. He often supervised the work from afar. |
| Marketing Experience |
|---|
| Pharmaceutical GMP manufacturing of APIs. |
| Other Relevant Experience |
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| He is an excellent writer with a background in journalism. He has organized and run large events. |
Fields of Expertise
active pharmaceutical ingredient, antitumor drug, cisplatin, applied inorganic chemistry, chemical processing, applied organic chemistry, bulk pharmaceutical chemical manufacturing, pharmaceutical manufacturing, chiral synthesis, asymmetric synthesis, applied inorganic chemistry, epoxide group, terpene synthesis, generic drug manufacturing, organic compound process development, pharmaceutical chemistry, heterocyclic chemistry, organic chemistry, organic synthesis, synthetic organic chemistry, education, controlled substance, terpene synthesis, boron trifluoride, carbohydrate chemistry, chirality, pharmaceutical industry, codeine synthesis, chemical reaction, chemical process safety, organophosphorus chemistry, chemical reaction mechanism, cancer chemotherapeutic agent, organometallic chemistry, inorganic synthesis, carbocation chemistry