Expert in Polyurethane (PU) Materials Development for various applications
In the past several years, her work has extensively involved development of polyurethanes for medical applications. The materials for medical applications need to meet a rigorous set of standards. As an example these materials must be non-toxic and biocompatible. For long-term implantation the materials also need to be biostable, resisting in-vivo degradation. Furthermore, the materials need to meet the specified application function.
In the past 5 years, Expert developed 3 different polyurethanes for surgical applications: 1) 2-component structural bone cement adhesive, 2) load-bearing surface for joint implants, and 3) porous foams for as scaffolding platform for tissue in-growth.
These materials are in different stages of development, with some of these products already receiving the FDA and CE approvals.
Over the past 30 years, Expert has developed and invented various polyurethane products that include rigid and flexible foams, elastomers, coatings, adhesives, sealants, etc. Her experiences in wide variety of polyurethanes often results in unique approach to product development. As an example, Expert was first to combine polyurethane foams with moisture-cured isocyanate resins to produce novel curable tapes used in medical immobilization and other applications.
The basic components in the synthesis of polyurethanes are isocyanates and polyols, which form urethane linkage. Under appropriate processing conditions, isocyanate may also form other linkages, such as urea, allophanate, biuret, isocyanurate, carbodiimide, uretdione, amide, imide, oxazolidone, etc.
In applications requiring good heat and thermal stability, polyurethane linkages are often not suitable as they starts to dissociate (break) at 100-140° C. Therefore, for higher temperature applications other linkages may be preferred such as urea, oxazolidone, isocyanurate, imide, etc.
The formation of these bonds is controlled by the selection of appropriate catalysts, reaction temperature, and composition of the starting components, etc. Expert has completed several studies of the kinetics and catalysis of formation of heat resistant groups, including oxazolidone, isocyanurate, and imides. The study on model reaction systems was extended to development of various heat resistant isocyanate-based products, such as isocyanurate foams, polyoxazolidone composites and coatings, polyimide foams, etc.
Evaluation of new type of cycloaliphatic isocyanate and its performance in polyurethanes. Development of new types of biodurable polyurethane foams for tissue in-growth application, their evaluation, preparation of foams and implants for in vitro-testing, including the development of various protocols for cleaning, sterilization, etc. Development of formulations and packaging for new type of bone cement for syrgical applications and assistance in various issues regarding in vitro and in vivo testing and EPA approval procedures
Expert may consult nationally and internationally, and is also local to the following cities: Detroit, Michigan - Warren, Michigan - Flint, Michigan - Sterling Heights, Michigan - Lansing, Michigan - Ann Arbor, Michigan - Livonia, Michigan - Dearborn, Michigan - Cleveland, Ohio - Toledo, Ohio
|Year: 1985||Degree: Ph.D.||Subject: Chemistry||Institution: University of Zagreb, Croatia|
|Year: 1978||Degree: Masters||Subject: Chemistry||Institution: University of Zagreb, Croatia|
|Year: 1972||Degree: BS||Subject: Chemistry||Institution: University of Sarajevo, Bosnia|
|Years: 2001 to Present||Employer: Undisclosed||Title: Research Director||Department:||Responsibilities: Coordinates and leads contract R&D efforts for development of wide range of polyurethane materials with tailored properties for biomedical, electronics, construction, automotive, space, chemical, and agricultural applications. Her expertises are in polyurethanes foams, elastomers, structural adhesives, immobilization casts, blocked-isocyanate heat activated products, clear polyurethane cast elastomers, and hydrophilic polyurethanes. In addition to application development, she is routinely involved in evaluation of new and novel raw materials for polyurethanes. She had also coordinated studies on the environmental stability of isocyanates.|
|Years: 1988 to 2001||Employer: University of Detroit Mercy||Title: Senior Research Scientist and Adjunct Professor||Department: Polymer Institute||Responsibilities: Conducted fundamental research and application development projects with focus on polyurethanes. These research efforts were primarily contract research projects sponsored by private sector and governmental agencies. She also coordinated research work of visiting scientists from around the globe and graduate students working on graduate thesis. Her area of research covered kinetics and mechanism of isocyanate-based reactions, structure-property relationship in polyurethane elastomers and foams (both rigid and flexible), development of heat resistant polymer properties (oxazolidone, isocyanurate, polyimides), fuel resistant foams, medical products (immobilization cast, artificial joints, drug release platform), acrylate/polyurethane blends, etc.|
|Years: 1974 to 1988||Employer: Academia and polyurethane industry, Bosnia and Herzegovina.||Title: Various senior positions||Department:||Responsibilities:|
|Years: 1994 to 1996||Agency: EPA||Role: Project coordinator||Description: She was project coordinator in the studies related to utilization of isocyanate binders in solidification of various types of waste materials (e.g.automotive shredder residue, fly ash, etc.)|
|Years||Country / Region||Summary|
|Years: 2004 to 2014||Country / Region: Puerto Rico||Summary: The development of new adhesive product for electronic application|
|Years: 1992 to 1994||Country / Region: Mexico||Summary: -Development of shoe adhesive-Consulting in spray systems for truck bedliners|
|Associations / Societies|
|American Chemical Society|
|Awards / Recognition|
|1.Two time - Best poster award at the API Polyurethanes Conference;
2..Best paper award at the Polyurethanes World Congress
3.Best paper award at the SPI Annual Polyurethane Conference
|Publications and Patents Summary|
|She has over 60 publications, 16 patents.
Two proceedings: Polyurethane Elastomers Workshops 2000, Polyurethane Elastomers Workshops 2001.
|Training / Seminars|
|She was principal organizer of Polyurethane Elastomer Workshop 2000 and 2002.|
|Continuosly searching suppliers of raw materials for polyurethane products, polyurethane products and application|
|- Formulation and packaging of new bone cement product;
- Specialty adhesives for electronics application;
- Immobilization casting with non-tack properties;
- Hydrophilic polyurethane products
|Other Relevant Experience|
|-Education of graduate student in polymers and thesis advisor;
-Training in laboratory skills and fundamentals in polyurethanes