Expert Details

Expert in Process Chemistry: R&D, GC, HPLC, Flash Chromatography, NMR, IR, Mass Spec, & LCMS, Synthetics

Expert ID: 724436 California, USA

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He has experience with process research and development, including scale-up to 10- and 15-L reactors. Included in his background is experience with the design, execution, and optimization of multi step organic syntheses aimed at both pharmaceutical intermediates and APIs. In addition, he has experience with chromatographic and spectroscopic methods: GC, HPLC, flash chromatography, NMR, IR, Mass Spec, and LCMS, and have experience with development of analytical methods. Furthermore, he has experience with preparation of SOPs for production of intermediates and products, and with preparation of validation documentation. Lastly he has experience training technicians and junior chemists in procedures and aspects of operations

Array

Developed a garage-scale production system for a friend that wanted to prepare his own biodiesel.Wrote four short white papers relating to interactions of light and matter for a client company.

Expert may consult nationally and internationally, and is also local to the following cities: San Jose, California - San Francisco, California - Sacramento, California - Oakland, California - Stockton, California - Fremont, California - Modesto, California - Salinas, California - Santa Rosa, California - Hayward, California

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Education

Year Degree Subject Institution
Year: 1984 Degree: MS Subject: Organic Chemistry Institution: University of Arkansas
Year: 1976 Degree: BS Subject: Chemistry Institution: Cal Poly, San Luis Obispo

Work History

Years Employer Title Department Responsibilities
Years: 2006 to Present Employer: Undisclosed Title: Process Chemist Department: ALOHA Responsibilities: Scale-up and development of methodologies and processes; Oversee and train technicians; Write SOPs, HazOps, and instructions on as needed basis;
Years: 2005 to 2006 Employer: A. P. Pharma Title: Sr. Research Associate Department: Responsibilities: Prepared samples of poly-ortho esters for research program in drug delivery systems
Years: 2005 to 2005 Employer: Nanosyn Title: Contract Scientist Department: Responsibilities: Prepared libraries of chemical compounds using combinatorial methods for pharmaceutical customers
Years: 2004 to 2005 Employer: Cytokinetics Title: Contract Scientist Department: Responsibilities: Scaled up synthetic sequences of small-molecule drug preparatory for in vivo testing program
Years: 2002 to 2003 Employer: Targesome Title: Contract Scientist Department: Responsibilities: Functionalized dextran to be used in liposome materials for drug delivery
Years: 2002 to 2002 Employer: Affymax Title: Research Associate Department: Responsibilities: Developed linkers to attach peptide pharmaceuticals to PEG; synthesized small-molecule pharmaceuticals
Years: 1997 to 2001 Employer: Catalytica Title: Process Research Chemist Department: Responsibilities: Developed processes for scale-up of synthetic sequences: pharmaceutical intermediates, impurity profiling, catalyst materials for asymmetric hyrogenation of chiral pharmaceuticals
Years: 1990 to 1997 Employer: Clontech Title: Sr. Research Associate Department: Responsibilities: Development and scale-up of production methods aimed at DNA modification reagents

International Experience

Years Country / Region Summary
Years: 1986 to 1987 Country / Region: United Kingdom Summary: Research on epoxide resins and modifiers for epoxide resins for aerospace applications

Career Accomplishments

Associations / Societies
ACS, AAAS
Publications and Patents Summary
Three publications and one patent related to synthetic oligonucleotides

Additional Experience

Vendor Selection
Experience developed over 20+ years in finding vendors/ suppliers as needed
Other Relevant Experience
Analysis and interpretation of NMR, GCMS, HPLC, and GC results; skills in writing SOPs, HazOps, work instructions; training of technicians and junior chemists

Language Skills

Language Proficiency
German Minor Proficiency

Fields of Expertise

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