Expert in Protein- and Peptide-Based Drug Discovery, Protein Assay Development, Cell Biology, and Immuno-Blot
Expert has performed genetic recombinants to develop new hybrid molecules. These genetic modifications confer unique physical properties to genes and their protein counterparts. These unique properties would be eventually used for their identification, isolation and purification.
Expert has used a standard molecular biological approach to develop many recombinant proteins and enzymes. He has also characterized them by either standard methods or by introducing modifications in the existing methods.
Expert is an expert in dealing with any protein-based methodology. He has published a unique modification of the Western blotting technique in the Journal of Immunological Methods. Western blotting is the confirmatory test used in the identification of HIV-infected individuals. He has the expertise to handle and/or advise on the structural and functional characteristics of proteins.
Expert is an expert in protein purification and downstream characterization. He has applied affinity, ion exchange, and gel filtration column chromatography to purify many proteins for clients including Sigma Chemical Co., USBiological, Roche Molecular Biochemicals and Tranzyme. He has developed and/or modified standard operating protocols for these clients.
Expert has generated several new methods and optimized many existing methods for protein research at Dr. Janet Brandsma's laboratory at Yale University.He has co-developed, with Stanley Stein of Rutgers University, a novel and proprietary drug delivery system and a novel peptide drug for Alzheimer's disease; two patents are pending on these inventions. He has also worked out the methodologies relating to the improvement of the technology.
Expert may consult nationally and internationally, and is also local to the following cities: New York, New York - Yonkers, New York - Newark, New Jersey - Jersey City, New Jersey - Paterson, New Jersey - Bridgeport, Connecticut - New Haven, Connecticut - Worcester, Massachusetts - Springfield, Massachusetts - Providence, Rhode Island
|Year: 1989||Degree: Ph.D.||Subject: Biochemistry and Molecular Biology||Institution: University of Madras, India|
|Year: 1986||Degree: M.Phil.||Subject: Biochemistry and Molecular Biology||Institution: University of Madras, India|
|Year: 1985||Degree: M.S.||Subject: Biochemistry and Molecular Biology||Institution: University of Madras, India|
|Year: 1982||Degree: B.S.||Subject: Chemistry||Institution: University of Madras, India|
|Years: 2000 to Present||Employer: Undisclosed||Title: President, CEO, and Director of Research||Department: Research and Marketing||Responsibilities: Expert developed by-products of research at Yale University and marketed them to the research community outside. He is also developing new research programs to attract NIH SBIR funding.|
|Years: 1999 to 2000||Employer: Yale University||Title: Associate Research Scientist||Department: Department of Epidemilogy and Public Health||Responsibilities: He produced protein subunit vaccines and conducted animal studies.|
|Years: 1996 to 1999||Employer: Yale University||Title: Associate Research Scientist||Department: Dept of Internal Medicine||Responsibilities: Expert performed research on liver disease animal models and cell culture to develop new protein expression systems.|
|Years: 1993 to 1996||Employer: Yale University||Title: Research Associate||Department: Section of Comparative Medicine||Responsibilities: He designed, produced, and studied the effect of gene vaccines on cotton tail rabbit papilloma virus, a rabbit model for human papillomavirus.|
|Years: 1990 to 1992||Employer: UMDNJ||Title: Research Associate||Department: Research Center||Responsibilities: Expert identified and characterized a golgi-bound enzyme called tyrosyl protein sulfotransferase. He also discovered that thios enzyme activity is elevated in the stomach of alcoholics and alcohol-fed rats.|
|Associations / Societies|
|In 1996, Expert was General Secretary of the Federation of Tamilsangams of North America (FeTNA), a non-profit, cultural organization.|
|Awards / Recognition|
|Expert’s awards and honors include: Graduate research fellowship through a national competitive test, from CSIR, New Delhi, India (1986-90); James Hudson Brown Alexander B. Coxe post-doctoral fellowship in medical sciences, Yale University, New Haven, CT (1994-95); Training Fellow, Molecular Virology and Oncology Training Program at
Yale University under Dr. Daniel C. Dimaio, M.D., Ph.D., Program Director (1995-96); recipient, Small Business Innovative Research Grant, Phase I (R43) from NCI, NIH (2001-03); and recipient, Small Business Innovative Research Grant, Phase I (R43) from NIA, NIH (2003-04).
|Publications and Patents Summary|
|He has three patents that are pending.|
|Tamil||Expert is fluent in Tamil.|