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RNA Polymerase, Antibacterial Agents, Antituberculosis Agents, Drug Discovery, Biodefense
Expert has experience working with bacterial complexes and transcriptions. He has worked in areas to of antibacterial agent sand antituberculosis as well. His work used tools of drug discovery and structural biology. Expert has Ph.D in Microbiology and Molecular Genetics…
Biology, Molecular Biology, Biochemistry
Since he started his career in science, Expert has been involved in projects that focus mainly on the characterisation of the function of specific proteins that are required in all the processes that involve nucleic acids in procaryotes and eucaryotes.…
Microbial Fermentation, Industrial Microbiology, Biotechnology
Expert. Expert has led fermentation and strain improvement efforts for a variety of anti-bacterial, anti-fungal, statins, ion-channel inhibitors, and immunoregulant natural products produced by actinomycetes and filamentous fungi. Expert led development of the Glarea lozoyensis fermentation process for producing Cancidas®,…
Recombinant Protein Expression/Production, Molecular Biology
Through an 18 year career at California Biotechnology, Scios Inc., and Johnson & Johnson, Expert has gained extensive experience in the molecular biology of recombinant protein production especially in microbial systems such as E. coli (inclusion body and soluble), Pichia…
Bioinformatics, Next-Generation Sequencing, SNP Analysis, Scientific Computing
The world of molecular biology is experiencing a deluge of quantitative data with the advent of new technologies such as high throughput sequencing, chromatin-immunoprecipitation sequencing, and RNA sequencing. New sequencing technologies are now producing sequence data at a very high…
Biotechnology, Biochemistry, Molecular Biology: Enzymology, Protein Biochemistry, Industry
As a researcher in plant molecular biology, he published scientific data relevant for genetic modification of crops. He generated and characterized genetically modified plants, and published these data in peer-reviewed scientific journals. This research, and tangential research, allowed him to…
Pharmaceutical & Life Science Research and Manufacturing, New Drug Discovery, Therapeutic Strategy
By using standard analytical tools of cellular and molecular biology he has elucidated the molecular mode of action of an anti-diabetic candidate BMOV on the key components of insulin signaling cascades like IR Kinase (IRK) and IRS complexes including gross…
Genomics
Expert worked with a team that cloned and expressed the enzyme T4 endonuclease VII for commercial distribution. He developed the basic assay of enzyme activity that was used in optimization and quality control of the enzyme. He is an author…
Protein Biochemistry, Purification, Characterization; Gentle Immunoaffinity Chromatography
Expert is internationally known for his contributions to the fields of biochemistry and molecular biology. He has worked in this area since 1964, generally in purifying enzymes involved in RNA synthesis, characterizing the structure and function of enzymes, and studying…