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Protein aggregation, characterization, purification
Expert leads a team of exceptionally talented downstream scientists to develop scalable downstream processes for viral vectors for use in Gene, Cell and Oncolytic therapies and for Vaccine production and for therapeutics proteins and antibodies. Keywords: Process development, DSP, Downstream…
Organic Chemistry, Analytical Chemistry, Biochemistry, Cell Biology, Photochemistry, Chromatography
Extensive experience in the identification of macromolecular interactions by site-directed photosensitized reactions. Monospecific antibodies and other protein ligands conjugated to visible light photosensitizers are powerful tools to demonstrate whether macromolecules and/or cellular organelles interact in situ and in vitro. Using…
Bionanosciences, Nanomaterial interfacing & targeting, Cell biology & biophysics, Molecular imaging, Microscopy
The expert has been actively designing and developing surface chemistries and coatings that allow a controlled organic/inorganic interfacing of colloidal nanomaterials with biomolecules. Over the past 14 years, projects carried out by the expert have focused on engineering the surface…
Immunology, Vaccinology, Infectious Diseases, Recombinant Proteins
Expert has been involved in numerous animal studies examining various aspects of infectious disease agents. Expert has worked with animal models of infection with the following diverse pathogens: Schistosoma mansoni, Candida albicans, Borrelia burgdorferi, and S. aureus. In addition, he…
Organic, Polymer and Surface Chemistry, Bioapplications and Separation Technologies
Expert designed and synthesized multifunctional surface chemistries for modification of glass, porous silica gels, carbon and various polymeric substrates in form of the membranes, micro particles, porous monolithic blocks, and capillaries. The following methods have been used for surface functionalzation:…
Biochemistry, Cell Biology
For over 25 years, Expert has been actively engaged in biochemical research either at the bench or in supervising a research group of about 10 technicians, students, and post-doctoral fellows. His biochemical expertise deals with carbohydrates, lipids, proteins, glycoproteins, and…
Enzyme and Protein Technology
Expert has devoted much of his career to derivatization of surfaces, development of methods for immobilization of ligands, and characterization of affinity matrices. He pioneered development of the technique of analytical affinity chromatography and has used this technique to characterize…
Protein Biochemistry, Purification, Characterization; Gentle Immunoaffinity Chromatography
Expert is internationally known for his contributions to the fields of biochemistry and molecular biology. He has worked in this area since 1964, generally in purifying enzymes involved in RNA synthesis, characterizing the structure and function of enzymes, and studying…