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Organic Chemistry, Analytical Chemistry, Biochemistry, Cell Biology, Photochemistry, Chromatography
Extensive experience in the identification of macromolecular interactions by site-directed photosensitized reactions. Monospecific antibodies and other protein ligands conjugated to visible light photosensitizers are powerful tools to demonstrate whether macromolecules and/or cellular organelles interact in situ and in vitro. Using…
Plant Biotechnology, Agiculture-Plant Breeding, Analytical Bbiochemistry- Mass Spectrometry
Expert having completed a post-doc and 12 years in academia went into the plant biotechnology industry at the very beginning. As such he has been involved in crop genetic engineering from the beginning with over 20 years of experience in…
Analytical Chemistry: HPLC, LC-MS, Bioanalysis. R&D projectmanagement; writing of publications
Expert’s scientific expertise includes the development, optimization and validation of quantitative bioanalytical methods for small molecules, peptides and biopharmaceutical drugs as well as for their metabolites in biological fluids (plasma, urine, tissue, etc.). These methods are essential for the pharma…
Metabolomics, Mass Spectrometry and Plant Pathology
Expert has developed expertise in metabolic reprogramming during susceptible and resistant interactions of Magnaporthe grisea with host plants, Brachypodium distachyon and rice as well as abiotic stress resistance in plants such as drought or cold tolerance. Such systems present many…
Proteomics, Mass Spectrometry, Cell Biology, Cancer Drug Targets Discovery
Expert has 15+ years of research experience in proteomics, cell and molecular biology and protein biochemistry. His main areas of expertise are large-scale analysis of protein expression and protein-protein interactions, protein phosphorylation analysis, signal transduction and biological mass spectrometry. Expert…
Drug Development (Small Molecules, Peptides, Biologics, Parenteral Nanoparticles); Drug Delivery
Expert is an expert in analytical instrumentation and analytical methods development and validation, especially for drug regulatory filings with the FDA and EMEA according to all FDA and ICH guidelines. He established a state-of-art core instrument department at Altus Pharmaceuticals…
Protein Chemistry & Regulation, Proteomics, Protein Mass Spectrometry, Proteases, Enzymology
Since 1990, Expert and his colleagues have analyzed proteins by electrospray or MALDI mass spectrometry to detect posttranslational modifications such as phosphorylation and fatty acylation. He has also been using it to detect genetic variants and to measure the precise…
Mass Spectrometry, HPLC/MS, Ion Trap MS, LC/MS/MS in Environmental, Food, Proteomic, and Pharmaceutical Analysis
Expert has been hired by law firms as an expert witness in the area of analytical chemistry. He has worked with 15 law firms in his career, with some of the cases going over multiple years. This experience includes: •…
Organic Synthesis, Bioorganic Chemistry, ESI; Biomedical, Agricultural Research
ORGANIC SYNTHESIS; TERPENE SYNTHESIS; ALICYCLIC COMPOUND; ALKALOID. Expert is experienced in most aspects of synthetic organic chemistry. He has experience in the synthesis of natural products including terpenoids, alkaloids, and alicyclic compounds. Expert is involved in the development of new…
Protein Biochemistry, Glycoproteins
Expert has spent much of his career involved in studies of the glycoprotein hormone family of gonadotropins. He has been involved in their protein chemistry, including purification of hormones and important natural fragments, primary structural work, and generation of antibodies.…