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Medicinal Chemistry/ Synthetic Organic Chemistry-Research and Patent Litigation
Experienced Medicinal Chemist and Consultant: expert at synthetic organic chemistry, pharmaceutical chemistry, pharmaceutical patent litigation, patent analysis: 1) Eight years of consulting experience, beginning in Jan. 2012, writing expert reports following patent analysis covering obviousness, claims validation, enablement; depositions given.…
Cancer Biology, Cell Biology, Molecular Biology, Signal Transduction in Mammalian Cells
Expert is a molecular biologist focused on cell signaling pathways that influence cancer initiation and progression. His work on the lipid kinase PI3K and AKT led to a number of highly cited articles and have contributed to the design and…
Hospital Tests and Kits, Clinical Chemistry, Coagulation, Serum Controls, Manufacturing Processes
Expert received his PhD in Biochemistry (Enzyme kinetics on NAD kinase in 1981), where he proposed a mechanism, Rapid Equilibrium Random with two dead end complexes for the enzyme, using enzyme inhibition studies. He was able to apply this knowledge…
Exercise Physiology, Fitness, Skeletal Muscle, Physiology, Thermoregulation, and Environmental Stress
The combination of Expert's experiences in basic and applied science, human, animal and clinical subjects, industry and academia, cellular biology and exercise physiology, in vivo and in vitro techniques, and teaching and research make her a uniquely qualified scientist. She…
Drug Discovery, Neuropharmacology, Serotonin, Dopamine, Antipsychotics, Pharma Project Management
Expert is an industrial neuropharmacologist with seventeen years of proven achievement in preclinical drug discovery of novel antipsychotics, antidepressants and analgesics (examples of drugs characterised: milnacipran, befiradol, F15599, F15063). He has significant expertise in serotonin receptor pharmacology, defining target selection…
Nutrition and Diabetes
Graduating from the University of Birmingham, UK with a B.Sc. in Biochemistry in 1983, this expert joined the Department of Biochemistry in the University of Oxford where he obtained a PhD in metabolic biochemistry in 1987. Moving to link signal…
Recombinant Protein Expression/Production, Molecular Biology
Through an 18 year career at California Biotechnology, Scios Inc., and Johnson & Johnson, Expert has gained extensive experience in the molecular biology of recombinant protein production especially in microbial systems such as E. coli (inclusion body and soluble), Pichia…
Protein Purification: Hands-on, Over 50 Projects Completed, Over 75 Proteins Purified
Expert has been actively involved in hands-on protein purification since 1985. Early work involved purification of enzymes and metal-binding proteins. From 1993 to 1997, as a Senior Scientist at a major biotech company, expert had very successfully developed methods for…
Neuroscience, Genetics, Gene Therapy, Biochemistry and Lab Equipment
Expert has expertise using and developing animal models for specific neurological conditions, from his work in gene therapy. In particular, Expert published the first gene therapy treatment that corrected a rodent model of Parkinson's disease, and has collaborated with two…
Structural Based Drug Design, Docking and MD Simulations, Chemoinformatics and Bioinformatics
Expert has extensive experience in designing small molecule drugs for oncology targets such as kinases. He can help you narrow down the number of compounds you are going search for a new drug by an efficient computational algorithm. He can…