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RNAi, Proteomics, Functional Genomics, Gene Expression, Automated Image Analysis
Expert. Expert's has 30 years of experience in the fields of developmental genetics, signal transduction and genomics. By developing, improving, and applying a number of genetic techniques (germline clones, FLP/FRT, Gal4/UAS, etc.), his group identified many key components of the…
Drug Discovery & Development Technology and Intellectual Property (Patents, Trade Marks, etc.)
He has had the Drug Discovery Department, as part of his role as Director R & D, at Wockhardt Limited, discover several new NCEs during the tenure of this position, which NCEs are more extensively described in a later section…
Pharmaceutical & Life Science Research and Manufacturing, New Drug Discovery, Therapeutic Strategy
By using standard analytical tools of cellular and molecular biology he has elucidated the molecular mode of action of an anti-diabetic candidate BMOV on the key components of insulin signaling cascades like IR Kinase (IRK) and IRS complexes including gross…
Protein Chemistry & Regulation, Proteomics, Protein Mass Spectrometry, Proteases, Enzymology
Since 1990, Expert and his colleagues have analyzed proteins by electrospray or MALDI mass spectrometry to detect posttranslational modifications such as phosphorylation and fatty acylation. He has also been using it to detect genetic variants and to measure the precise…