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Pharmaceutical and Biopharmaceutical Product Development, Formulation and Stabilization Technology
Expert has fifteen years of experience in product development, formulation development, and drug delivery for pharmaceutical and diagnostic industries. She has thoroughly developed skills in research planning, product formulation, and analytical problem solving. Expert has expertise in the fields of…
Protein Purification: Hands-on, Over 50 Projects Completed, Over 75 Proteins Purified
Expert has been actively involved in hands-on protein purification since 1985. Early work involved purification of enzymes and metal-binding proteins. From 1993 to 1997, as a Senior Scientist at a major biotech company, expert had very successfully developed methods for…
Nanotechnology, Biomaterials, Sol-gel Sciences, Optics, Biotechnology, Glass, Ceramics, Spectroscopy
Expert is a specialist of sol-gel chemistry. He developed a new non-aqueous method for sol-gel glass coating to obtain transparent films for integrated optics and photonics using polysiloxane materials. The aim was to obtain low-softening temperature glasses to permit facile…
Nanobiotechnology, Drug Delivery Platforms, Medical Devices, Targeted Therapeutics, Diagnostics
Expert has extensive experience establishing R&D operations in early stage biotechnology companies. He applied his knowledge in nano(bio)technology to develop innovative solutions to drug delivery and drug targeting challenges. His efforts to enhance the use of biomaterials in a variety…
Orphan Drugs: FDA/EU/Canada; FDA Approval; Drug Development: CMC, QA, QC, Manufacturing
12 product approvals from FDA including 6 new chemical entities, a 510k device, and three major pharmaceutical efficacy indication supplemental approvals. All received 5-10 years of regulatory exclusivity (Hatch-Waxman, Orphan Drug). These products are generating over $100 million dollars in…
Pharmaceutical & Life Science Research and Manufacturing, New Drug Discovery, Therapeutic Strategy
By using standard analytical tools of cellular and molecular biology he has elucidated the molecular mode of action of an anti-diabetic candidate BMOV on the key components of insulin signaling cascades like IR Kinase (IRK) and IRS complexes including gross…
Biomedical and Pharmacokinetic Modeling and Programming
Expert has performed experimental work in biochemistry for his doctoral thesis. This work included isolation of mitochondria from Neurospora crassa and rat liver, isolation and purification of membrane proteins by electrophoresis and reverse-phase chromatography, gel electrophoresis and use of radioactive…
Organic, Polymer and Surface Chemistry, Bioapplications and Separation Technologies
Expert designed and synthesized multifunctional surface chemistries for modification of glass, porous silica gels, carbon and various polymeric substrates in form of the membranes, micro particles, porous monolithic blocks, and capillaries. The following methods have been used for surface functionalzation:…
Virology, Anti-infectives, Gene Therapy, Bioterrorism Research
He has extensive experience in the development and use of viral vectors for gene transfer and in particular has worked with both adenovirus and AAV vector delivery systems. His work with adenovirus vectors included some of the earliest research focused…
Protein Structure, Biotechnology, Botany
He has expertise in plant identification, particularly nuisance waterweeds. Experience in waterweed control for duckweeds: Lemna, Wolffia, Spirodela, Landoltia and Wolffiella. He has expertise in the use of thaumatin and miraculin. Experience in purification, manipulation and storage of these flavor…