Expert Details
Organic Synthesis, Organometallics, Prostaglandins, Vitamin D, Catalysis
ID: 108405
Delaware, USA
ASYMMETRIC SYNTHESIS; ENANTIOSELECTIVE CATALYSIS. With his research group, he has developed new methods for the enantioselective preparation of organic intermediates. He has 30 years of direct research experience and a thorough working knowledge of the relevant chemical literature. He is also an expert in prostaglandin synthesis.
TRANSITION-METAL-MEDIATED ORGANIC REACTIONS. Expert and his research group have developed several new methods for transition-metal-mediated carbon-carbon formation.
CATALYSIS. Expert and his research group have developed several new methods for transition metal complex catalysis of organic reactions. They have experience in computer-based modeling of transition metal complexes and transition states, and in the use of those techniques to design improved catalysts.
He has worked with a major pharmaceutical company on improving the yield of Rh-mediated labeling.He has worked with the chemical process department of a major pharmaceutical company on developing new synthetic routes to desired chemical compounds. He has worked with a diversified chemical manufacturer on improving the manufacturing process for a catalyst.He has worked with the chemical process department of a major pharmaceutical company on improving the enantioselectivity of a synthesis.
Education
| Year | Degree | Subject | Institution |
|---|---|---|---|
| Year: 1974 | Degree: PhD | Subject: Organic Chemistry | Institution: Columbia University |
| Year: 1970 | Degree: BS | Subject: Chemistry | Institution: Stanford University |
| Year: 1975 | Degree: Postdoctoral | Subject: Asymmetric Organic Synthesis | Institution: University of Wisconsin |
Work History
| Years | Employer | Title | Department |
|---|---|---|---|
| Years: 2013 to 2018 | Employer: University of Delaware | Title: Professor Emeritus | Department: |
Responsibilities:reading, writing about organic synthesis |
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| Years | Employer | Title | Department |
| Years: 1993 to 2013 | Employer: University of Delaware | Title: Professor | Department: |
Responsibilities:organic synthesis research group |
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| Years | Employer | Title | Department |
| Years: 1984 to 1993 | Employer: University of Delaware | Title: Associate Professor | Department: |
Responsibilities:organic synthesis research group |
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| Years | Employer | Title | Department |
| Years: 1982 to 1984 | Employer: University of Delaware | Title: Assistant Professor | Department: |
Responsibilities:organic synthesis research group |
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| Years | Employer | Title | Department |
| Years: 1977 to 1982 | Employer: Vanderbilt University | Title: Assistant Professor | Department: |
Responsibilities:organic synthesis research group |
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Government Experience
| Years | Agency | Role | Description |
|---|---|---|---|
| Years: 1982 to Present | Agency: Department of Defense | Role: Consultant | Description: |
International Experience
| Years | Country / Region | Summary |
|---|---|---|
| Years: 1986 to 2000 | Country / Region: Japan | Summary: Several trips, visiting universities, participating in scientific meetings. |
| Years: 1987 to 2000 | Country / Region: Western Eurpoe | Summary: Several trips, visiting universities, participating in scientific meetings. |
| Years: 1993 to 1999 | Country / Region: PRC | Summary: Two trips, visiting universities, participating in scientific meetings. |
| Years: 2000 to 2000 | Country / Region: Poland | Summary: One trip, visiting a research institute, participating in a scientific meeting. |
| Years: 1997 to 1997 | Country / Region: Thailand | Summary: One trip, participating in a scientific meeting. |
Career Accomplishments
| Associations / Societies |
|---|
| He is a member of the American Chemical Society and the American Association for the Advancement of Science. |
| Professional Appointments |
|---|
| He is a Reviewer: Journal of the American Chemical Society, Journal of Organic Chemistry, Organic Letters, Tetrahedron Letters and Tetrahedron. |
| Awards / Recognition |
|---|
| He is a Fellow of the American Association for the Advancement of Science and has received Research Grants from NIH, NSF and Petroleum Research Fund. |
| Publications and Patents Summary |
|---|
| He has published 205 research papers on organic synthesis and organometallic catalysis, five book chapters, four monographs, and two undergraduate laboratory textbook. He is the author of the weekly online resource Organic Highlights |
Additional Experience
| Expert Witness Experience |
|---|
| He has served as an expert witness on patent cases, including preparing expert witnesses, participating in depositions, and testifying. 1. 1992-93 Expert witness Chemical valuation of petroleum distillates; testified at hearing 2. 1993-94 Expert witness Chemical processes: methods for preparing diltiazem; deposed, testified at ITC hearing 3. 2000 Expert Witness Chemical nomenclature of prostaglandin derivatives; expert report, deposed. 4. 2000 Expert Witness Chemical nomenclature of prostaglandin derivatives 5. 2000-01 Expert Witness Chemical processes: methods for preparing quinolone antibiotics; expert report, deposed. 6. 2007 Expert Witness Prostaglandin derivatives expert report, deposed 7. 2009 Expert Witness, expert report, case settled 8. 2010 Expert Witness, Vitamin D derivatives; case settled. 9. 2011 Expert Witness, 10. 2014-2015 Department of Justice: Duty classification of imported chemicals 11. 2015 prostacyclin derivatives 12. 2016 roflumilast expert report, deposed 13. 2017 consultation 14. 2017 tetracycline synthesis claim construction |
| Training / Seminars |
|---|
| He has taught Intermediate Organic Chemistry, a bridge between the undergraduate and the graduate course, at several industrial sites in this area, usually in groups of 15 or 20 at a time. |
| Other Relevant Experience |
|---|
| He is an expert in the use of computational methods to design organometallic catalysts. |
Language Skills
| Language | Proficiency |
|---|---|
| French | |
| German | |
| Japense |
Fields of Expertise
asymmetric synthesis, catalysis, enantioselective catalysis, natural product, organic chemistry, organic reaction, organic synthesis, palladium, transition-metal-mediated organic reaction, transition metal catalysis, transition metal catalyst, chemical intermediate, enantiomer, metallic element, enantioselective heterogeneous catalysis, palladium homogeneous catalysis, acid catalysis, alcohol compound, chemical reagent, precious metal, Friedel-Crafts reaction, molecular chirality, atropine, cyclopentene, cyclopentadiene, hexachloroethane, scopolamine, transition element chemistry, platinum chemistry, osmium chemistry, hafnium chemistry, samarium chemistry, silver chemistry, palladium chemistry, rhodium chemistry, ruthenium chemistry, zirconium chemistry, copper chemistry, cobalt chemistry, manganese chemistry, chromium chemistry, titanium chemistry, tetrahydrofuran, organic reaction mechanism, phenolic compound, diene, drug, organic compound, terpene, zirconium, tropane, transition element, terpene synthesis, stereochemistry, shape-selective catalysis, samarium, rhodium, quinone, qualitative organic chemistry, polystep catalysis, piperidine, organometallic compound, organometallic chemistry, organic acid, nitrogen organic compound, natural organic compound, morphine, lanthanum, hydrocarbon chemistry, heterocyclic compound, halogenated hydrocarbon, glycol compound, europium, ethylene oxide, dibasic organic acid, crown ether chemistry, cobalt, catalytic oxidation, catalytic hydrogenation, catalyst, catalysis reagent, carbocation chemistry, carbanion chemistry, caffeine, biradical, biochemistry, asymmetric induction, aromatic hydrocarbon, aromatic acid, amine, amide, alkaloid, aliphatic polyene, aliphatic hydrocarbon, aliphatic acid, aldehyde, acid