Expert Details

Expert in Drug Delivery Technologies;Therapeutic Polymers; Biomaterials

Expert ID: 731940 Massachusetts, USA

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Expert is the Principal and Consultant at a consulting company. The company provides advisory and consultancy services in the areas of drug discovery, therapeutic polymers and biomaterials. He has extensive experience in these areas and co-invented eight therapeutic polymers to reach clinical trials, three of which are approved worldwide (Renagel, Renvela, and Welchol/Cholestagel). He is an inventor on 72 issued US patents and the author of more than 30 publications in these areas. His clients include small and large pharma companies, startups, venture capital firms, and government agencies.

Prior to this he was a Co-Founder and the Chief Technology Officer at a large biomaterials and neuroscience company. He was responsible for helping start it and fulfill its corporate objectives of providing research and development of biomaterials as drug delivery systems for epilepsy, spinal cord injury, pain, and Parkinson's disease. Expert was responsible for developing the technical approaches, hiring the initial team of scientists and engineers, and leading the R&D efforts.

Before the neuroscience company, he was a Vice President and Distinguished Scientific Fellow at Genzyme. For several years, he led the Therapeutic Polymer and Biomaterial Portfolio of research programs. In that role, he was responsible for managing multiple biomaterial and polymer research programs (classified as both drugs and devices), handling the budgeting and prioritization for the programs, and developing new programs. He co-invented many therapies at Genzyme, and was extensively involved in intellectual property and regulatory filings, including presenting technical data to the FDA, and representing Genzyme in two trials relating to generic competitors. He participated on the internal review committee which oversaw the technical aspects of all Genzyme research programs. He also has experience in market assessment, target validation, test method development (in vivo and in vitro), candidate evaluation, and development of drug product profiles.

Expert was the second employee of GelTex Pharmaceuticals, a startup with the mission to develop therapeutic polymers. Genzyme acquired GelTex in 2000 for ~ $1.25 billion, largely based on the value of two therapeutic polymers that he co-invented (Renagel and Welchol). He rose to the position of Director of Chemical Research where he led the chemistry effort to develop novel therapeutics.

Expert also has experience in applied research involving polymer interfaces, surface chemical bonding, and adhesives from his jobs at GTE Laboratories and Lord Corporation.

Expert holds a Ph.D. degree in Chemistry from Harvard University where he studied the surface science of polymers, and a BA with a dual major in Chemistry and Biology from Cornell University.


Expert may consult nationally and internationally, and is also local to the following cities: Boston, Massachusetts - Worcester, Massachusetts - Springfield, Massachusetts - Lowell, Massachusetts - Cambridge, Massachusetts - Brockton, Massachusetts - New Bedford, Massachusetts - Hartford, Connecticut - Manchester, New Hampshire - Providence, Rhode Island

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Education

Year Degree Subject Institution
Year: 1986 Degree: PhD Subject: Chemistry Institution: Harvard University
Year: 1982 Degree: BA Subject: Chemistry and Biology Institution: Cornell University

Work History

Years Employer Title Department Responsibilities
Years: 2012 to Present Employer: Undisclosed Title: Consultant Department: Responsibilities: Consulting in the areas of drug delivery, therapeutic polymers, biomaterials, drug discovery
Years: 2013 to 2014 Employer: PixarBio Corporation Title: Co-Founder and Chief Technology Officer Department: Responsibilities: He was responsible for helping start PixarBio and fulfill its corporate objectives of providing research and development of biomaterials as drug delivery systems for epilepsy, spinal cord injury, pain, and Parkinson's disease. He was responsible for developing the technical approaches, hiring the initial team of scientists and engineers, and leading the R&D efforts.
Years: 2000 to 2012 Employer: Genzyme Title: vice President and Distinguished Scientific Fellow Department: Responsibilities: He led the Therapeutic Polymer and Biomaterial Portfolio of research programs. In that role, he was responsible for managing multiple biomaterial and polymer research programs (classified as both drugs and devices), handling the budgeting and prioritization for the programs, and developing new programs. He co-invented many therapies at Genzyme, and was extensively involved in intellectual property and regulatory filings, including presenting technical data to the FDA, and representing Genzyme in two trials relating to generic competitors. He participated on the internal review committee which oversaw the technical aspects of all Genzyme research programs. He also has experience in market assessment, target validation, test method development (in vivo and in vitro), candidate evaluation, and development of drug product profiles.
Years: 1992 to 2000 Employer: GelTex Pharmaceuticals Title: Director of Chemical Research Department: Responsibilities: He was the second employee of GelTex Pharmaceuticals, a startup with the mission to develop therapeutic polymers. Genzyme acquired GelTex in 2000 for ~ $1.25 billion, largely based on the value of two therapeutic polymers that he co-invented (Renagel and Welchol). Expert rose to the position of Director of Chemical Research where he led the chemistry effort to develop novel therapeutics.

Career Accomplishments

Associations / Societies
American Chemical Society Polymer Division Fellow, American Institute for Medical and Biological Engineering College of Fellows, National Kidney Foundation of Northern California Honoree, IBM Predoctoral Fellowship in Polymer Science
Awards / Recognition
American Chemical Society Team Innovation Award, Industrial Innovations Award by Northeast Region of American Chemical Society, American Chemical Society/Polymer Chemistry Division Industrial Sponsors Award, R&D 100 Award from R&D magazine, Sherwin Williams Award in applied polymer science.


Publications and Patents Summary
Co-inventor of a variety of technologies resulting in 70 issued US patents and worldwide equivalents and 35 publications in the areas of pharmaceuticals, therapeutic polymers, adhesives, and surface chemistry. A comprehensive list is available upon request.

Fields of Expertise

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