Expert Details

Expert in Medical Oncology-Drug Development/ Strategy and Biomarker/ Theranostics

Expert ID: 736427 Massachusetts, USA

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He has nearly two decades of experience in oncology and drug development. He is currently leading the clinical sciences program for a biotech company focused on CAR-T therapy for cancer. Before that, he served as the Director of Phase I Clinical Research at Beth Israel Deaconess Medical Center in Boston and faculty at Harvard Medical School. In addition, he has advised several small and mid-cap pharmaceutical companies and cancer biomarker companies over the last decade. He also served as an expert medical oncology reviewer for a state medical board and as an expert medical witness for medical malpractice cases.

He is Board certified in medical oncology; he has completed numerous clinical trials with investigational agents, a few of which have received FDA approval for certain cancers. He has also received research funding from several organizations and several awards.

He has published over 200 peer-reviewed articles and abstracts in journals such as the New England Journal of Medicine, Journal of Clinical Oncology, Clinical Cancer Research, and Cancer Cell. He is on the editorial board of three journals and has served as an ad hoc reviewer for over 10 science and medical journals. He is also proud to have mentored many students over the years on laboratory or clinical research projects. In addition, he has given over 50 invited lectures both nationally and internationally.

Medical Oncologist/ drug development/ theranostics expertise with almost two decades of experience in clinical care, clinical trials. Medical expert witness for medical malpractice.

Education

Year Degree Subject Institution
Year: 2013 Degree: MBA Subject: Business Administration Institution: W.P. Carey School of Business, Arizona State University
Year: 2001 Degree: MD Subject: Medicine Institution: Sackler School of Medicine/Tel Aviv University, Ramat Aviv, Israel
Year: 1997 Degree: BA Subject: Biological Sciences, Cum Laude Institution: Rutgers College, Rutgers University

Work History

Years Employer Title Department
Years: 2020 to Present Employer: Undisclosed Title: VP, Clinical Sciences Department:
Responsibilities:
CAR-T, drug development
• Clinical/medical lead for the BOXR1030 drug program, working and meeting regularly with the clinical operations, research, regulatory, and translational research team members.
• Meet with research team, medical science liaison, and clinical operations business development team members for companies under the Employer umbrella and provide feedback from an early phase oncology perspective.
• Oversee direct reports on the clinical team and outside consultants supporting the BOXR programs’ clinical development.
Years Employer Title Department
Years: 2019 to 2020 Employer: Unum Therapeutics Title: Senior Medical Director Department:
Responsibilities:
• Sponsor medical monitor for ATTCK-34-01 phase I trial: Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers. For this trial, worked with and met regularly with study, product, and translational research team members and the study’s CRO representatives, reviewed and approved subject enrollment packets, reviewed and edited study safety reports, reviewed and edited study amendments and publications, reviewed TLFs and CSRs, and liaised with trial site investigators.
• Was the clinical/medical lead for the BOXR1030 drug program, working and meeting regularly with the clinical operations, research, regulatory, and translational research team members, reviewed and edited FDA INTERACT submission, reviewed and edited publications and study synopsis, reviewed and summarized competitive intelligence, and led discussion/proposal for starting dose rationale and study design.
• Met regularly with research team and business development team leaders to review potential business development opportunities and provide feedback from early phase oncology perspective and assisted with presentation and drafting of proposals to outside interested parties.
• Met regularly with research team members for early preclinical drug candidate selection, reviewing and providing feedback on in vitro and in vivo data presentations to help inform phase I trial design.
Years Employer Title Department
Years: 2020 to Present Employer: Undisclosed Title: Medical Consultant Department:
Responsibilities:
theranostics
Years Employer Title Department
Years: 2018 to 2019 Employer: Harvard Medical School Title: Faculty Department:
Responsibilities:
(Associate Professor appointment was still under review when resigned)
Medicine
Years Employer Title Department
Years: 2018 to 2019 Employer: Beth Israel Deaconess Medical Center Title: Attending Physician Department:
Responsibilities:
Available upon request.
Years Employer Title Department
Years: 2013 to 2019 Employer: UACOM-P (non-voting) Title: Clinical Associate Professor Department:
Responsibilities:
Medicine
Years Employer Title Department
Years: 2013 to 2017 Employer: Western Regional Medical Center at Cancer Treatment Centers of America® Title: Attending Physician Department:
Responsibilities:
Available upon request.
Years Employer Title Department
Years: 2013 to 2017 Employer: Western Regional Medical Center at Cancer Treatment Centers of America® (WRMC) Title: Director Department:
Responsibilities:
Clinical Research
Years Employer Title Department
Years: 2013 to 2017 Employer: WRMC Title: Director Department:
Responsibilities:
Phase I&II Clinical Trials
Years Employer Title Department
Years: 2012 to 2017 Employer: TGen Title: Translational Physician Scientist Department:
Responsibilities:
Available upon request.
Years Employer Title Department
Years: 2011 to 2015 Employer: Cancer Research and Biostatistics Title: Chief Medical Officer Department: Lung Cancer Research Team
Responsibilities:
Available upon request.
Years Employer Title Department
Years: 2008 to 2013 Employer: University of Arizona College of Medicine-Phoenix (UACOM-P) Title: Clinical Assistant Professor Department:
Responsibilities:
Medicine
Years Employer Title Department
Years: 2009 to 2017 Employer: TGen Title: Adjunct Clinical Associate Professor Department:
Responsibilities:
Cancer & Cell Biology
Years Employer Title Department
Years: 2009 to 2013 Employer: Scottsdale Healthcare Title: Associate Clinical Investigator Department:
Responsibilities:
Available upon request.
Years Employer Title Department
Years: 2007 to 2013 Employer: Scottsdale Healthcare Title: Director Department:
Responsibilities:
Thoracic Oncology, Virginia G. Piper Cancer Center Clinical Trials
Years Employer Title Department
Years: 2007 to 2014 Employer: The Translational Genomics Research Institute (TGen) Title: Co-Head Department: Lung Cancer Unit, Cancer & Cell Biology Division
Responsibilities:
Available upon request.
Years Employer Title Department
Years: 2007 to 2009 Employer: The Translational Genomics Research Institute (TGen) Title: Assistant Professor Department:
Responsibilities:
Cancer & Cell Biology
Years Employer Title Department
Years: 2007 to 2009 Employer: Scottsdale Healthcare Title: Assistant Clinical Investigator Department:
Responsibilities:
Available upon request.

Career Accomplishments

Associations / Societies
American Society of Clinical Oncology (ASCO):
Member
Member, Cancer Education Committee-Lung Cancer Track Member, TAPUR Clinical Trial Tumor Board Member,
Professional Development Committee Mentor, ASCO Virtual Mentorship Program

International Association for the Study of Lung Cancer (IASLC):
Member
Member, Career Development & Fellowship Committee
Co-Chair, Career Development & Fellowship Committee
Member, Membership Committee
Member, Strategic Committee

American Association for Cancer Research (AACR):
Member
Member, Mentored Grants & Research Fellowship Scientific Review Committee

American Association for the Advancement of Science (AAAS):
Member
Licenses / Certifications
MA Medical License
Medical Oncology Board Certification
ABIM Certification, Medical Oncology
NBPAS Certification, Internal Medicine and Medical Oncology
Professional Appointments
Scientific Advisory Board, Amgen
Scientific Advisory Board, Blend Therapeutics
Scientific Advisory Board, International Genomics Consortium
Scientific Advisory Board, Angiex
Medical Advisor and Board Member, Phoenix Cancer Support Network (PCSN) (non-profit)
Conference Chair, Annual New Treatments in Oncology Conference
Phase I Clinical Research, Beth Israel Deaconess Medical Center (BIDMC)
Board Member, Phoenix Cancer Support Network

Committee Service:
Protocol Review Monitoring Committee, University of Colorado Health Sciences Center (UCHSC)
Fellowship Selection Committee, UCHSC
Medical School Interviewing Committee, University of Arizona College of Medicine-Phoenix
Imaging Probes of Tumor Vulnerability Committee, The Translational Genomics Research Institute
Institutional Review Board F, Dana-Farber/Harvard Cancer Center
Fellowship Selection Committee, Beth Israel Deaconess Medical Center
Awards / Recognition
- Bloustein Distinguished Scholar Award, Pre-doctoral Scholarship
- Merit Scholarship Award, Rutgers University, Pre-doctoral Scholarship
- Phi Beta Kappa, Rutgers University, Pre-doctoral Scholarship
- Molecular Biology in Clinical Oncology Workshop Scholarship, - American Society of Clinical Oncology (ASCO)/ American Association for Cancer Research (AACR), Travel funds and post-doctoral workshop
- Methods in Clinical Cancer Research Workshop Scholarship, ASCO/AACR, Travel funds and post-doctoral workshop
- Young Investigator, Southwest Oncology Group, Travel funds and post-doctoral workshop
- Young Investigator Award, International Association for the Study of Lung Cancer (IASLC), Travel funds
- Travel Grant Award, European Society of Medical Oncology (ESMO)/IASLC, Travel funds
- Young Investigator Travel Grant, ESMO, Travel funds
- ASCO Leadership Development Program, ASCO, One of 16 selected for this competitive program
Medical / Professional
Internship: Internal Medicine: SUNY-Downstate, Brooklyn, NY
Residency: Internal Medicine: SUNY-Downstate, Brooklyn, NY
Fellowship: Hematology/Medical Oncology: University of Colorado Health Sciences Center (UCHSC)
Chief Fellow: Hematology/Medical Oncology: UCHSC, Aurora, CO

Publications and Patents Summary
Funded and Unfunded Projects: 77 since 2006
Local Invited Presentations: 10 since 2007
Regional, National, and International Invited Teaching and Presentations: Regional (16) National (35) International (16)
Peer Review Publications: 95
Proceedings of meetings or other non-peer reviewed scholarship: 2
Reviews, chapters, monographs and editorials: 31
Case Reports: 11
Letters to the Editor: 7
Books and Book Chapters: 4
Abstracts, Poster Presentations and Exhibits Presented at Professional Meetings: 168 total posters

Additional Experience

Expert Witness Experience
Medical expert witness/consultant, Medical malpractice cases since 2017
Marketing Experience
Editorial Activities, Ad Hoc Reviewer:
Cancer Research
Clinical Cancer Research
Cancer Letters
Drug Discovery Today
Journal of Thoracic Oncology
Lung Cancer
Therapeutic Advances in Medical Oncology
EMBO Molecular Medicine
Cancer Prevention Research
Oncogene
Cancer Chemotherapy and Pharmacology
International Journal of Cancer
Expert Opinion on Orphan Drugs
PLoS ONE
Cancer

Editorial Boards:
MicroRNA
Cancer Medicine
Integrative Cancer Science and Therapy
Integrative Molecular Medicine
Translational Lung Cancer Research
Other Relevant Experience
Consulting Experience:
Scientific Advisor, Circulogene
Consultant, Ignyta
Consultant, Angiex
Medical Advisor, IBEX Medical Analytics
Consultant, Spring Bank Pharmaceuticals
Consultant, Exact Sciences (after Paradigm/Viomics acquisition)
Consultant, Genomic Health
Consultant, Imaging Endpoints
Scientific and Medical Advisor, Viomics (company sold)
Medical Oncology Consultant, Arizona Medical Board
Consultant, Pharmatech
Scientific and Medical Advisor, Paradigm Diagnostics (company sold)

Fields of Expertise

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