Expert Details

Expert in Medicinal Chemistry, Drug Discovery, Organic Chemistry, Antibody-Drug Conjugates

Expert ID: 731784 California, USA

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Accomplished project leader with strong experience as R & D medicinal chemist in advancing projects from inception to Phase I clinical trials in ocular, inflammation, diabetes and neuroscience areas. Skilled in medicinal chemistry, organic chemistry, small molecule and peptide lead optimization, bioconjugation, and antibody drug conjugates. Expertise in leading cross-functional teams for drug discovery projects. Advanced three projects to Phase I and three projects to candidate nomination stage.

Core competencies include: Oncology, neuroscience, diabetes research. Project leader in matrix environment. Managed and directed chemistry projects at CROs. Co-led Portfolio Optimization Committee and launched new projects. Modern synthetic & medicinal chemistry. Drug discovery and biology knowledge. Small molecule and peptide medicinal chemistry. Outsourcing Project Management and External Relationship Development.


Worked with Ignyta on their chemistry needs (2013)Currently working with two biotech companies (2014-- ).

Expert may consult nationally and internationally, and is also local to the following cities: Los Angeles, California - San Diego, California - Long Beach, California - Santa Ana, California - Anaheim, California - Riverside, California - Glendale, California - Huntington Beach, California - San Bernardino, California - Chula Vista, California

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Education

Year Degree Subject Institution
Year: 1989 Degree: Ph.D. Subject: Medicinal Chemistry Institution: The University of Kansas

Work History

Years Employer Title Department Responsibilities
Years: 2008 to 2013 Employer: Pfizer Title: Senior Principal Scientist Department: Chemistry, CovX division Responsibilities: He identified new targets and launched new drug discovery projects. He led a multi-disciplinary team of scientists to advance projects to Phase I. He was a project leader for diabetes and long acting human growth hormone projects. He was responsible for developing new peptide delivery platform technology
Years: 2006 to 2008 Employer: TargeGen Title: Principal Scientist IV Department: Medicinal Chemistry Responsibilities: He advanced projects to Phase I by working with scientists in ocular and oncology area
Years: 1994 to 2006 Employer: Celgene Title: Group Leader Department: Medicinal Chemistry Responsibilities: He was senior chemist on AP-1 NFkB, IKK2 projects
He was project leader for Neuroscience and PKC theta projects
He was head of compound library generation group and compound library management and distribution group
Years: 1992 to 1994 Employer: La Jolla Pharmaceuticals Title: Scientist II Department: Chemistry Responsibilities: Lead chemist and worked on LJP-394, a drug for treating systemic lupus erythematosus.

International Experience

Years Country / Region Summary
Years: 2003 to 2007 Country / Region: India Summary: Worked with a CRO in India

Career Accomplishments

Associations / Societies
A member of American Chemical Society
A member of American peptide society
Licenses / Certifications
Currently enrolled in Project Management Certificate program at UCSD, Cornerstones of Management 1(A) - Delivering Results
Professional Appointments
Reviewer for chemistry and medicinal chemistry journals
Publications and Patents Summary
27 papers, 27 posters and oral presentations, 18 patents (applications and issued).

Additional Experience

Training / Seminars
Management Training, Managing People, Project Management - Planning, Scheduling & Controlling Projects, Matrix Management - Project Leader Management Training
Vendor Selection
Developed and established working relationship with vendors in San Diego, Germany, China and India.
Managed and directed chemistry efforts at CROs
Marketing Experience
Expert. Expert has wealth of knowledge in biotechnology sectors. He currently consults two biotech companies with their needs

Language Skills

Language Proficiency
Tamil
Telugu

Fields of Expertise

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