Expert Details

Expert in Molecular Immunology, Antigen-Antibody Interactions, Immunochemistry, etc.

Expert ID: 107881 Ohio, USA

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ANTIGEN-ANTIBODY INTERACTION. Expert has studied the physico-chemical and biological consequences of interactions between monoclonal antibodies and bacterial polysaccharides, viral glycoproteins, or molecules of the major histocompatibility complex. His work suggests new strategies for the engineering of more effective antibodies.

IMMUNOCHEMICAL ASSAY. In his research and clinical laboratory experience, Expert has employed radioimmunoassays, enzyme-linked immunosorbent assays, flow cytometry, and microlymphocytoxicity assays. He has experience with a wide variety of solid-phase immunoassay formats.

IMMUNOCHEMISTRY. In the course of his studies on interactions between monoclonal antibodies and a bacterial polysaccharide antigen, Expert has evaluated equilibrium and kinetic constants. He has devoted substantial effort to understanding and clarifying the molecular basis for antibody specificity.

HUMORAL IMMUNOLOGY. Expert's published work has addressed some of the factors that influence the effectiveness of antibodies in mediating humoral immunity. In studies in progress, these vaccines are composed of a polysaccharide (or oligosaccharide) covalently attached to a carrier protein.


Expert may consult nationally and internationally, and is also local to the following cities: Detroit, Michigan - Warren, Michigan - Livonia, Michigan - Dearborn, Michigan - Cleveland, Ohio - Toledo, Ohio - Akron, Ohio - Youngstown, Ohio - Canton, Ohio - Erie, Pennsylvania

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Education

Year Degree Subject Institution
Year: 1981 Degree: PhD Subject: Immunology Institution: University of Pennsylvania
Year: 1981 Degree: MD Subject: Medicine Institution: University of Pennsylvania
Year: 1975 Degree: AB Subject: Biochemical Sciences Institution: Harvard University

Work History

Years Employer Title Department Responsibilities
Years: 1993 to Present Employer: Undisclosed Title: Associate Professor of Pathology Department: Responsibilities:
Years: 1986 to 1993 Employer: Case Western Reserve University Title: Assistant Professor Of Pathology Department: Responsibilities:
Years: 1986 to Present Employer: Undisclosed Title: Director, Clinical Histocompatibility Laboratory Department: Responsibilities:
Years: 1981 to 1986 Employer: Washington University, Barnes Hospital, St. Louis, MO Title: Resident in Laboratory Medicine Department: Responsibilities:
Years: 1982 to 1985 Employer: Washington University, St. Louis, MO Title: Postdoctoral Fellow of Department of Microbiology and Immunology Department: Responsibilities:

Career Accomplishments

Associations / Societies
Expert is a member of the American Association for the Advancement of Science, the American Association of Immunologists, the American Association of Pathologists and the Clinical Immunology Society.
Publications and Patents Summary
He has published 23 papers and contributed to seven books. Expert has presented many invited lectures.

Fields of Expertise

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