Expert Details

Expert in Toxicology, Environmental Medicine, Biochemistry, Cancer Causation, DNA Damage & Repair, Genetics, Arsenic, Metals

Expert ID: 724866 New York, USA

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Expert has published about 120 articles, mostly on metal carcinogenesis and environmental toxicology, with an emphasis on arsenic. She was first to report on the comutagenicity of arsenic and later developed the only animal model of arsenic-induced skin cancer. She established that arsenic compounds affect the genetic mutation process in unconventional ways, such as inhibition of DNA repair. She participated in the International Agency for Research in Cancer (IARC) review of the carcinogenicity of metals, Lyon, France, 19XX and again in 20XX. Expert organized and chaired the session on mechanisms of carcinogenesis at the NIH/EPA meeting “Arsenic: Health Effects, Mechanisms of Action, and Research Issues”. She was co-organizer of the First, Second, and Third International Meetings on Molecular Mechanisms of Metal Toxicity and Carcinogenicity. In 20XX, Expert edited a Special Issue of Mutation Research devoted to Metals and Carcinogenesis. She was a member of the Scientific Advisory Board (arsenic) for the USEPA. She has been a consultant and expert witness for the legal profession.

In other research, Expert studied the toxicology of environmental agents such as ultraviolet light, chromium, nickel, and other metals. Expert has been an expert witness in food contamination.

Expert has served on a number of Federal Committees to determine risk and mechanism of toxicity of a number of toxicants. She has also consulted for industry and for the legal profession on issues of toxicology. Expert has served on the Chemical Pathology Study Section (NIH), the National Toxicology Program Study Section, the American Cancer Society Study Section (Genetics), twice on the Environmental Health Sciences Review Committee (NIEHS), on NIH Small Business Grants (Genetics) study section, and on the Metabolic Pathology Study Section (NIH). She served on the editorial boards of Environmental and Molecular Mutagenesis, Mutation Research, Molecular Toxicology, and Teratogenesis, Carcinogenesis and Mutagenesis, and is a reviewer for many other journals as well as Federal documents.

She wrote background papers on the role of arsenic compounds in human disease (risk assessments) for a class action lawsuit involving environmental arsenic exposure. In this case, she worked for the defense, and was able to show that the various diseases listed by plaintiffs were not associated with arsenic exposure, but had other causes.For the plaintiff in a case of food contamination causing chemical burn to the mouth, she developed a PowerPoint presentation showing that, contrary to defense's position, there was a very substantial level of contaminant that was enough to cause the burn.She analyzed whether a particular exposure scenario might have contributed to the lung disease in a plaintiff who, it was claimed, had an immune deficiency. She showed that, in fact, the alleged immune deficiency had not been proved.She advised on a case of childhood exposure to a contaminated playground, and examined data of the chemicals found. Among these chemicals were three that had a causal link to the disease in the plaintiff. (Still ongoing).She arranged to have an attorneys office tested for x-ray leakage from a chemotherapy office downstairs. The results showed that there was no leakage.

Expert may consult nationally and internationally, and is also local to the following cities: New York, New York - Yonkers, New York - Newark, New Jersey - Jersey City, New Jersey - Paterson, New Jersey - Elizabeth, New Jersey - Bridgeport, Connecticut - New Haven, Connecticut - Hartford, Connecticut - Springfield, Massachusetts

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Education

Year Degree Subject Institution
Year: 1968 Degree: Ph.D. Subject: Basic Medical Sciences Institution: NYU School of medicine
Year: 1965 Degree: Subject: Biochemistry Institution: Brandeis University
Year: 1964 Degree: A.B. Subject: Biology/Chemistry Institution: N.Y.U. College of Arts and Sciences

Work History

Years Employer Title Department Responsibilities
Years: 1971 to Present Employer: Undisclosed Title: Professor Department: Responsibilities: She is a Principle Investigator on research grants from the NIH, EPA, and other agencies, having published over 120 articles on environmental causes of disease. Her research focus is on metals and radiation and deals mainly with cancer. She also teaches, acts as an editor of scientific journals, and serves on federal and international committees that evaluate causes of disease.
Years: 1969 to 1971 Employer: Bellevue Hospital Title: Postdoctoral Fellow Department: Dept. of Pathology Responsibilities: Research on liver tumors in rats, chief of Pathology

Government Experience

Years Agency Role Description
Years: 1980 to 1985 Agency: National Institutes of Health Role: Member, study section Description: She served as a member of the National Institute of She served as a member of the Environmental Health Sciences Special Study Section, which reviews Center grants, Program Projects, and Training Grants.
Years: 1993 to 1996 Agency: National Institutes of Health Role: Member, study section Description: She served as a Member of the Metabolic Pathology Study Section, which reviewed Research Grants.
Years: 2007 to 2007 Agency: Agency for Toxic Substances and Disease Registry (ATSDR) Role: Peer-reviewer Description: She reviewed the Draft Provisional Peer-Reviewed Toxicity Value Manuscript for Antimony (Soluble Compounds and Antimony Trioxide).
Years: 2005 to 2006 Agency: USEPA Role: Science Advisory Board Description: She was a Member of the USEPA Science Advisory Board on Arsenic.

International Experience

Years Country / Region Summary
Years: 1993 to 2009 Country / Region: Lyon, France Summary: At various times, she served on a World health Organization expert panel (International Agency for Research on Cancer) that met at their headquarters in Lyon, France. The purpose of these panels was to determine whether specific chemicals should be considered human carcinogens.

Career Accomplishments

Associations / Societies
She is a member of: Society of Toxicology, Environmental Mutagen Society, American Association of Cancer Research, and American Chemical Society.
Professional Appointments
Director, Molecular and Genetic Toxicology, Department of Environmental Medicine, NYU-Langone School of Medicine, Director, Molecular Toxicology and Carcinogenesis, Department of Environmental Medicine, NYU-Langone School of Medicine
Chairperson, Graduate Student Recruitment Committee, Department of Environmental Medicine, NYU School of Medicine
Science Advisory Board (Arsenic), US Environmental Protection Agency (USEPA)
NIH study section member, various times
Awards / Recognition
Woman of Achievement, Orange County, NY
Publications and Patents Summary
She has over 120 published full length papers and book chapters and many more abstracts.

Additional Experience

Expert Witness Experience
She has been an expert witness in a case involving chemically-induced damage to an individual by a contaminant. She has also served as a "behind the scenes" expert in a number of cases involving environmental and occupational exposures to toxicants. She has prepared reviews on toxicants and causes of diseases written for the lay audience, and has responded to statements by the opposing Toxicologist, as well as given depositions.
Training / Seminars
Developed the first graduate course in Genetic Toxicology in the New York metropolitan area. This deals with effects of environmental agents on genes.
Developed and taught a course for patent lawyers on Recombinant DNA.
Organized the Hudson Valley Science cafe.
Marketing Experience
Has some knowledge of preclinical testing for pharmaceuticals.
Other Relevant Experience
Her special expertise is writing about scientific and medical issues for the lay person. She has published many text book chapters on toxicants. She has great skill in developing PowerPoint presentations that explain scientific ideas to a lay audience, including juries.

Language Skills

Language Proficiency
French She has slight proficiency in reading and speaking French.

Fields of Expertise

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