Expert Details

Expert in Cancer Biology, Cell Biology, Molecular Biology, Signal Transduction in Mammalian Cells

Expert ID: 731136 Canada

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Expert is a molecular biologist focused on cell signaling pathways that influence cancer initiation and
progression. His work on the lipid kinase PI3K and AKT led to a number of highly cited articles and have contributed
to the design and development of new cancer treatment therapies. As more clinical trials demonstrating the efficacy
of targeted cancer therapies emerge, it is becoming clear that some of the most hopeful treatments are now within
our reach. Cancer still has the advantage, however, and current thought is that combinatorial drug therapies that
converge treatment modalities will provide superior efficacy. As a specialist in understanding how kinases function,
Expert is positioned to identify and exploit these signaling enzymes. More recently, he has discovered a new
interaction in cancer between two of the most often activated proteins, the kinase AKT and the transcription factor
MYC. The interaction between AKT and Myc could represent an important and novel cancer target, as small
molecules designed to disrupt their interaction could have significant clinical benefits.

Multiple

Education

Year Degree Subject Institution
Year: 1999 Degree: PhD Subject: Molecular Biology Institution: University of British Colombia
Year: 1993 Degree: BSc Subject: Biochemistry Institution: University of Guelph

Work History

Years Employer Title Department Responsibilities
Years: 2009 to Present Employer: Undisclosed Title: Associate Professor Department: Responsibilities:
Years: 2004 to 2009 Employer: York University Title: Assistant Professor Department: Responsibilities:
Years: 1999 to 2004 Employer: Ontario Cancer Institute Title: Postdoctoral Fellow Department: Cell Signalling Responsibilities:
Years: 1994 to 1999 Employer: University of British Colombia Title: Graduate Research Assistant Department: Responsibilities:

Government Experience

Years Agency Role Description
Years: 2012 to 2012 Agency: CIHR Role: Member, Cancer Biology and Therapeutics, Grant review panel (volunteer). Description: He was a committee member of this scientific panel that meets twice per year to adjudicate operating grants submitted to the CIHR. As a member, he was responsible for reviewing 8 operating grants and presenting his assessments during a two-day meeting in Ottawa.

Career Accomplishments

Associations / Societies
PROFESSIONAL MEMBERSHIPS
2005 – 2007 Member, American Society for Microbiology
2012 – Present Member, American Society for Microbiology
Professional Appointments
Cancer Research Society grant review panel
CIHR Grant review panel
Awards / Recognition
2008 – 2011 Early Researcher Award MRI/York $50,000/year
2005 – 2010 New Investigator Award CIHR $50,000/year
2000 – 2003 Postdoctoral Fellowship CIHR $38,000/year
2000 – 2003 Postdoctoral Fellowship NCIC (declined) $38,000/year
2000 – 2002 Postdoctoral Fellowship NSERC (declined) $30,000/year
2000 Postdoctoral Fellowship AMGEN $33,000
1997 – 1999 Doctoral Fellowship CRS $15,000/year
Publications and Patents Summary
Expert has 24 journal publications, 8 published reviews, and 11 published abstracts.

Fields of Expertise

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