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A significant portion of Expert's research in food chemistry and nutrition has involved the development of analytical methods for various vitamins and their metabolites in foods and biological materials. This work has primarily involved the application of HPLC, with particular attention to problems such as sample extraction, purification, and derivatization. He also has considerable experience in analytical methodology of proteins, enzymes, carbohydrates, dietary fiber, and lipids.

Expert has a broad working knowledge and research experience in many aspects of food chemistry, including kinetics, enzymology, vitamin stability, chemical deterioration (browning reactions, lipid oxidation, etc.), and the chemical basis of food preservation.

A majority of Expert's research career has been focused upon chemical, analytical, and nutritional aspects of folic acid or folate. He has significant experience in the chemical synthesis and isotopic labeling of various folates. He is adept in the development and use of HPLC methods for determination of folates in foods and biological materials, and in analytical uses of folate-binding proteins. His studies concerning folate bioavailability and metabolism have focused on digestive processes, as well as the application of radioisotopic and stable-isotopic methods for assessment of in-vivo vitamin metabolism and vitamin-dependent metabolic processes.


Expert has studied the chemistry, analysis, bioavailability, and metabolism of vitamin B6. A major accomplishment of his in this research is the development of HPLC methods that permit the determination of free and glycosated forms of the vitamin. In the context of research on vitamin B6 bioavailability and metabolism, he has gained extensive experience in the use of radioisotopic and stable-isotopic methods for in-vivo studies. This research has yielded important new information regarding the incomplete bioavailability of naturally-occurring glycosated forms of vitamin B6.


Expert's research group has been a leader in the development and application of stable-isotopic methods for the study of vitamin bioavailability and metabolism. This is a major advance in nutrition research because it provides an alternative to the use of radioisotopes for isotopic studies with human subjects. They have developed methods for the specific labeling and GCMS quantitation of folates and vitamin B6 compounds with deuterium. He also has extensive experience in the use of these compounds and many other metabolic tracers in nutrition research.

In studies concerning bioavailability and metabolism, Expert's research has involved extensive preparation and in-vivo use of radiolabeled (tritium and carbon-14) forms of vitamin B6 and folates. Through these studies, he has also gained significant experience in the experimental use of radioisotopically-labeled nutrients.


Expert's entire research career has focused primarily on chemical, analytical, and nutritional aspects of vitamins. Although his major research emphasis and expertise centers on folate and vitamin B6, his expertise extends broadly over the area of water-soluble vitamins. He is well-versed in analysis by spectral, ligand binding, and chromatographic methods, especially HPLC. He also has a broad knowledge of vitamin stability and experience in matters relating to food fortification and nutritional labeling.

Expert's expertise includes nutrition and the nutritional properties of foods. His research career has mainly emphasized various nutritional and metabolic aspects of B-vitamins in humans and animals.


Expert has conducted research on factors affecting the bioavailability of vitamins, mainly folate and B6, in humans and animals. He has also studied the effects of food composition and chemical form of the nutrient, as well as the development and use of radioisotopic and stable-isotopic methods. Expert is familiar with the chemistry of dietary fiber and modern analytical methods regarding dietary fiber.

His research concerning nutritional aspects of B-vitamins has focused on studies of bioavailability and metabolism in humans and animals using stable-isotopic and radioisotopic methods.

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