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Molecular Immunology, Antigen-Antibody Interactions, Immunochemistry, etc.
ANTIGEN-ANTIBODY INTERACTION. Expert has studied the physico-chemical and biological consequences of interactions between monoclonal antibodies and bacterial polysaccharides, viral glycoproteins, or molecules of the major histocompatibility complex. His work suggests new strategies for the engineering of more effective antibodies. IMMUNOCHEMICAL…
Molecular Biology, Molecular Pathology, Polymerase Chain Reaction Technology
Expert has expertise in the adaptation and development of molecular biological techniques to answer medical questions of human genetics, differential gene expression, diagnostics, epidemiology, and pathogenesis, particularly in regard to infectious agents and genetic diseases. The CGS is a multidisciplinary…
Protein Biochemistry, E Coli Mutation, Thioredoxins, Amino Acid Residues, etc.
Expert has expertise in the purification and characterization of disulfide-containing redox proteins from a variety of micro-organisms. She has used the standard techniques of both low and high pressure chromatography on ion exchange and size exclusion gels. She is also…
Protein Biochemistry, Glycoproteins
Expert has spent much of his career involved in studies of the glycoprotein hormone family of gonadotropins. He has been involved in their protein chemistry, including purification of hormones and important natural fragments, primary structural work, and generation of antibodies.…